lions 52, jaguars 6

Jared Goff threw two of his four touchdown passes to Amon-Ra St. Brown, David Montgomery and Jahmyr Gibbs combined for three rushing touchdowns, and Detroit routed Jacksonville on Sunday.

The Lions have won eight straight and nine of their first 10 games in a season for the first time since 1934.

Detroit’s winning margin of 46 points was the largest in franchise history, and it handed Jacksonville its biggest-ever defeat. The Lions also set a franchise record in total yards with 644.

The Jaguars have lost four consecutive games for the second time this season.

Jacksonville rookie Cam Little made a career-best 59-yard field goal on the game-opening drive and closed the first half with another field goal.

In between those kicks, the Lions scored four touchdowns to take a 28-3 lead.

saints 35, browns 14

Taysom Hill capped a 138-yard, three-touchdown performance on the ground with a 75-yard scoring run, and New Orleans improved to 2-0 under interim coach Darren Rizzi with a victory over Cleveland.

Hill’s two other touchdowns went for 10 and 33 yards — the second on fourth and short — to more than balance out his two turnovers on an interception and fumble. The 34-year-old Hill also moved into ninth place in franchise history with 44 total TDs, four behind receiver Eric Martin.

Hill also completed an 18-yard pass and returned a kickoff 42 yards.

vikings 23, titans 13

Sam Darnold overcame an early fumble by throwing for 246 yards and two touchdowns and running for a score as Minnesota beat Tennessee.

Darnold had been picked off five times over the previous two games, matching his total over the first seven games of the season. Then his toss to Aaron Jones on the Vikings’ third offensive play was fumbled and recovered by Jeffery Simmons for the Titans.

The quarterback answered right back to help the Vikings win their third straight and improve to 5-0 against AFC teams this season. He found Jordan Addison for a 47-yard catch-and-run touchdown as the Vikings didn’t trail again by scoring 16 straight for a 16-3 halftime lead.

colts 28, jets 27

Anthony Richardson ran for a 4-yard touchdown, his second of the game, with 46 seconds left in his return to the starting role to lift Indianapolis to a victory over New York.

With the Jets leading 27-22 after Anders Carlson’s 35-yard field goal with 2:41 remaining, Richardson — benched for two games in favor of Joe Flacco — marched the Colts down the field.

dolphins 34, raiders 19

Tua Tagovailoa threw three touchdown passes, De’Von Achane ran for a score, and Miami beat Las Vegas to win their second straight game.

It was another strong victory for the Dolphins, who have not matched their offensive fireworks from last season but are coming off a gritty win over the Rams last Monday. The Raiders lost their sixth straight.

Tagovailoa led the Dolphins down the field with long, methodical drives — three of them more than seven minutes — that all ended in scores.

rams 28, patriots 22

Matthew Stafford threw for 295 yards and four touchdowns, including a 69-yard score to Cooper Kupp on the second play of the second half to help Los Angeles pull away from New England.

The patriots trailed 14-10 after Rams kicker Joshua Karty’s 26-yard field-goal attempt at the end of the first half clanged off the right upright. Los Angeles received the kick to start the second half, and on second down Stafford found Kupp near midfield; Patriots cornerback Jonathan Jones dove for the pass and missed, leaving no one between Kupp and the end zone.