Greg Gumbel, a longtime CBS sportscaster who broke barriers during his career calling some of the biggest sporting events, has died from cancer, according to a statement from his family released by the network on Friday. He was 78.

“He leaves behind a legacy of love, inspiration and dedication to over 50 extraordinary years in the sports broadcast industry; and his iconic voice will never be forgotten,” wife Marcy Gumbel and daughter Michelle Gumbel said in a statement.

In March, Gumbel missed his first NCAA Tournament since 1997 due to what he said at the time were family health issues.

Gumbel was the studio host for CBS since returning to the network from NBC in 1998. Gumbel signed an extension with CBS last year that allowed him to continue hosting college basketball while stepping back from NFL announcing duties.

In 2001, he announced Super Bowl 35 for CBS, becoming the first Black announcer in the U.S. to call play-by-play of a major sports championship.

David Berson, president and CEO of CBS Sports, described Gumbel as someone who broke barriers and set standards for others during his years as a voice for fans in sports, including in the NFL and March Madness.

“A tremendous broadcaster and gifted storyteller, Greg led one of the most remarkable and groundbreaking sports broadcasting careers of all time,” Berson said.

Gumbel had two stints at CBS, leaving the network for NBC when it lost football in 1994 and returning when it regained the contract in 1998.

Sean McManus said of all the moves he made in his nearly 27 1/2 years leading CBS Sports, one of his proudest was bringing Gumbel back.

“Not only did he elevate our NFL and NCAA coverage to a new level, but his kindness, generosity, sense of humor and unselfishness were second to none. When he was around, he made everyone from the researchers to the technicians to the executives feel like he was their best friend,” said McManus, who retired as CBS Sports chairman in April. “His love for his family was always the foundation of his life. There will never be another Greg Gumbel, and our industry and this world is a sadder place without him.”

Gumbel hosted CBS’ coverage of the 1992 and 1994 Winter Olympics and called Major League Baseball games during its four-year run broadcasting the national pastime. In 1995, he hosted the world figure skating championships and the following year hosted NBC’s daytime coverage of the Atlanta Summer Olympics.