Cisco Systems Inc. has agreed to acquire Waltham-based CloudLock Inc., a cloud-security provider, for $293 million in cash and equity.

The deal is a major windfall for the venture capital backers, who invested about $35 million, including Bessemer Venture Partners in New York and Ascent Venture Partners and Cedar Fund in the Boston area.

CloudLock was founded in 2007 but changed course in 2011 to focus on cloud technology. San Jose, Calif.-based Cisco Systems said CloudLock will add to its security portfolio, for cloud-based technology on various devices.

“Together, we plan to offer the industry’s broadest cloud security protection and enable our customers to realize the benefits of the mobile-cloud era,’’ Cisco said in a press release.

CloudLock has 134 employees. “There are no plans to relocate the CloudLock team,’’ according to Cisco spokeswoman Ella Nevill.

In a blog post, Luke Burns of Ascent Venture wrote that CloudLock founder and first-time chief executive Gil Zimmermann “crushed it.’’ He and his cofounders, Ron Zalkind and Tsahy Shapsa, were “early to identify the opportunity to provide security for companies transitioning to the cloud,’’ Burns said.

The acquisition is expected to close in the first quarter of fiscal 2017. Cisco shares were up over 1 percent near midday, at $27.66.

Beth Healy can be reached at beth.healy@globe.com. Follow her on Twitter @HealyBeth.