Operation quick turnaround.

Frustrated and hogtied 48 hours earlier in a loss in Ottawa, the Bruins came back smoking hot Wednesday night at the Garden, scored four goals in the first period, and pinned a 6-1 loss on the Red Wings that included two goals each by Brad Marchand and David Krejci.

“Playing behind their defense is one thing we wanted to change,’’ said Boston coach Bruce Cassidy, now 9-3-0 since taking over the bench a month ago after Claude Julien’s dismissal. “And we did . . . give the guys credit . . . we played much better in the netural zone. Response. Throughout this stretch here, any adversity, whether it a penalty kill, a call we don’t agree with, a goal against, a tough shift . . . we’ve asked them to respond, keep looking forward and playing.’’

The only hitch in their swing vs. the Wings came in the opening minutes of the first period, Detroit with a 7-2 shot lead in the opening eight minutes.

But then . . . the deluge.

The Bruins went on to score four in a row — two by Krejci, one by Marchand, and another by newcomer Drew Stafford — in a span of only 8:38. Game over. Marchand potted his second (No. 32 on the season) late in the second, and then David Pastrnak joined the victory march at 0:34 of the third, bumping it to 6-1.

For the ninth time in 12 games under Cassidy, the Bruins scored first. They led for a total 48:53, adding to their massive time advantage in the 12 games: 406:40 to 103:04.

In general, they get ahead and stay ahead, and marry that to a resilient attitude that has them shaking off rather than dwelling on whatever adversity comes their way. Essential qualities for a club yet to secure a playoff berth, although what a month ago looked like a lost cause is now looking like an inevitable postseason invite.

“We didn’t start great,’’ noted goalie Tuukka Rask, whose early stops, when the Red Wings showed some strut, were essential to his 31st victory. “Hey, we realize the situation we’re in . . . there’s not that many games [15] left.’’

The four-goal barrage, the club’s strongest under Cassidy, was only a surprise in that the Wings came out with that strong initial burst after playing the night before in Toronto. They had a 7-2 shot lead by the 8:00 mark and might have had a one- or two-goal lead if not for some alert work by Rask. Over the final 12 minutes of the first period, the Bruins clicked off 13 straight shots (the Wings frozen at seven), and piled up their lead on the goals by Krejci, Marchand, and Stafford.

All the goals were at even strength. All were with the Red Wings making a mess of things in their own end with mismanagement on the scale of Lehman Brothers.

Krejci (with his first three-point game this season) opened it up at 11:07 when he burned by Danny DeKeyser on the right wing, the Wings defenseman befuddled on a long pass by Stafford. DeKeyser didn’t know whether to cut it off or to take out Krejci. His indecision left Krejci to zip by him, collect the puck, and pick apart starting goaltender Jared (Score-O) Coreau for the 1-0 lead.

Only 1:01 later, Marchand knocked in the 2-0 lead, sent in alone by a long flip from center ice by Pastrnak. The Li’l Ball o’ Hate was left with easy pickin’s, slipping in his 14th goal in the last 17 games. Consecutive shots, consecutive goals, and Coreau was reeling at 12:08.

Stafford ended Coreau’s night at 13:32, trailing Pastrnak and snapping in a short-range roof shot after his linemate lost the puck off a Niklas Kronwall poke check. Stafford had his first goal in a Spoked-B uniform and Coreau had himself a red carpet to the showers. Petr Mrazek took over the Detroit net, Coreau having made but five stops on eight shots.

“They couldn’t take that one away from me,’’ mused Stafford, who saw his first goal in a Boston uniform wiped off the board last week when he was charged with goalie interference. “I am happy to be here, hoping to be part of the solution.’’

Finally, with only 15 seconds remaining in the first period Krejci jumped on another turnover deep in the Detroit end and potted his second of the night (18th of the season).

The middle period was far tamer, but the Bruins added to the beating at 16:55 on Marchand’s second of the night. Yet another Red Wings defensive breakdown, this time with Colin Miller sending him in alone from just outside the blue line. The shifty Marchand stuffed home No. 32 (five under his career high last year) with a forehand stuff under Mrazek’s right pad.

The Wings interrupted the humility with 2:25 remaining in the second, Kronwall connecting for his first goal this season with a long-range knuckling slapper that caught the crossbar and bounced in behind Rask to cut it to 5-1.

Finally, Pastrnak jumped on the victory parade, sniping in the 6-1 lead with only 34 seconds gone in the third period. He broke off the bottom third of his stick on the shot, and with the lower portion dangling from the shaft, he skated to the sideboards and eased it over the glass to a young girl in the loge.

The fan treated it like it was a gift fallen from hockey heaven. The Bruins are 6-1 at the Garden under Cassidy, and the Gallery Gods are smiling.

Kevin Paul Dupont can be reached at kevin.dupont@globe.com. Follow him on Twitter @GlobeKPD.