Chase Hunter had 20 points and six assists, and West Region No. 6 seed Clemson held off third-seeded Baylor for a 72-64 victory in the second round of the NCAA Tournament on Sunday in Memphis.

The Tigers advanced to the Sweet 16 for the second time in coach Brad Brownell’s 14 seasons.

Joseph Girard III had 13 points for the Tigers (23-11).

Next up for Clemson is No. 2 seed Arizona.

RayJ Dennis led Baylor with 27 points, including 21 in the second half. Ja’Kobe Walter added 20 points, but the Bears (24-11) lost in the second round for the third straight year.

ALABAMA 72, GRAND CANYON 61 >> Mark Sears had 26 points and 12 rebounds, Mouhamed Dioubate scored all nine of his points in the final 51/2 minutes, and the fourth-seeded Crimson Tide to beat the No. 12 seed Lopes in Spokane.

Alabama (23-11) advances to the Sweet 16 for the 10th time overall and third time in the last four seasons under coach Nate Oats.

Tyon Grant-Foster scored 29 for Grand Canyon (31-4).

Midwest Region

PURDUE 106, UTAH STATE 67 >> Zach Edey had 23 points and 14 rebounds, and the No. 1 seed Boilermakers cruised into the Sweet 16 by pounding the eighth-seeded Aggies in Indianapolis.

Purdue (31-7) which broke the school’s single-season record for victories. Braden Smith had all six of his assists in the second half when the Boilermakers shot 65.2% from the field before pulling the starters.

Purdue also set a school record for most points in a March Madness game. Next up is fifth-seeded Gonzaga in the regional semifinals in Detroit.

Great Osodor had 14 points and six rebounds for Utah State (28-7).

South Region

MARQUETTE 81, COLORADO 77 >> In their third season under coach Shaka Smart, the second-seeded Golden Eagles (27-9) reached the Sweet 16 for the first time since 2013 by outlasting the 10th-seeded Buffaloes (26-11) in Indianapolis.

Kam Jones scored 18 points for Marquette, which shot 61.8% from the field but still couldn’t shake Colorado until the closing seconds. Chase Ross made a tiebreaking 3-pointer with 2:53 left.

KJ Simpson scored 20 points and Tristan da Silva had 17 for Colorado, which trailed by 11 at halftime but rallied to take a 55-54 lead just over five minutes into the second half. Tyler Kolek put the Golden Eagles back on top with a short jumper and Marquette never trailed again, but Colorado tied it twice, the last time on a 3-pointer by da Silva with 4:02 remaining.

The Buffs trailed 79-77 and had to foul three times before putting David Joplin on the line for a 1-and-1. He knocked down both and set up a regional semifinal meeting with No. 11 seed North Carolina State.

DUKE 93, JAMES MADISON 55 >> Jared McCain scored 22 of his 30 points in the first half and set a school record for an NCAA Tournament game with eight 3-pointers as the fourth-seeded Blue Devils ended the 12th-seeded Dukes’ dream season with a victory at Barclays Center in Brooklyn.

Duke (26-8) is headed to the Sweet 16 to face Houston or Texas A&M.

McCain and Duke emphatically ended the nation’s longest active winning streak at 14 games.

The Dukes (32-4) finished with a program record for victories.

East Region

UCONN 75, NORTHWESTERN 58 >> The top overall seed Huskies overwhelmed the ninth-seeded Wildcats (22-12) to sail into the Sweet 16.

Tristen Newton had 20 points and 10 assists, and Donovan Clingan finished with 14 points, 14 rebounds and eight blocks as UConn (33-3) became the first defending national champions to reach the regional semifinals since Duke in 2016.