TUCSON, Ariz. >> Defensively, there wasn’t much to complain about with the Colorado women’s basketball team on Sunday.

The offense was another story.

A plethora of missed shots and turnovers led to the 21st-ranked Buffaloes being routed by No. 18 Arizona, 61-42, on Sunday at the McKale Center.

CU (21-6, 12-4 Pac-12) had a five-game winning streak snapped, but remains in third place in the conference, one game ahead of Arizona (21-6, 11-5) and 1.5 games ahead of UCLA (21-6, 10-5), which plays at Stanford on Monday.

Tameiya Sadler led the Buffs with 12 points, while Quay Miller posted another double-double (10 points, 10 rebounds).

Overall, the Buffs had their lowest-scoring game of coach JR Payne’s seven-year tenure, posting a season-low shooting percentage (28.3%), including 1-for-12 from 3-point range. They also racked up 20 turnovers for the second game in a row after not hitting that mark since late November.

“It just felt very jumbled from beginning to end,” Payne said. “Our effort was there, but just no rhythm, no sync.”

The Wildcats completed an impressive weekend, as they also rolled past No. 4 Utah on Friday. Shaina Pellington led the way Sunday with 19 points and five assists.

For the second year in a row, the Buffs lost by 19 in Tucson, and in both games the Buffs got uncharacteristically rattled.

Miller had six points and six rebounds in the first 6 minutes of the game, helping CU to a 10-7 lead. She had just four points and four rebounds the rest of the way, however.

Arizona went on a 14-0 run to take a 21-10 lead in the first minute of the second quarter. During that stretch, the Buffs went 0-for-10 from the floor and mixed in a pair of turnovers.

“Our pace was not as good as we needed it to be,” Sadler said. “With all the turnovers and we weren’t converting and us missing layups, that was just an open window for them. That was just devastating for us.”

CU’s four top scorers — Miller, Aaronette Vonleh, Frida Formann and Jaylyn Sherrod — struggled all day. That quartet came in averaging 48.3 points per game, but finished with 20 points on 8-of-36 shooting (22.2%).

“We missed a lot of layups early and free throws, things that we normally make,” Payne said.

“When you get those kinds of looks, you work for them, you get them and then we’re not able to convert, I think that makes you frustrated. It makes you maybe a little bit more hesitant, just kind of playing in a state of frustration, which we haven’t done all year.”

As a team, the Buffs were 12-of-30 (40%) on layups and 11-of-18 (61.1%) on free throws.

Despite that, a 3-pointer by Sadler pulled the Buffs within 33-25 with 6:07 to play in the third. Arizona quickly responded, however, with a game-changing 15-0 run to take a 23-point lead. The Buffs were 0-of-5 with five turnovers in that stretch.

“They kept scoring, which was hard for us to really find a rhythm to keep playing,” Sadler said. “I think that pulled us apart from each other instead of bringing us all together and feeling like we can go out there and continue to battle.”

Sadler and Kindyll Wetta did spark a 12-1 run that cut that deficit to 12 early in the fourth, but that’s as close as the Buffs got down the stretch.

Notable

With a 70-62 win at Arizona State on Friday, the Buffs earned a split for the weekend. … CU’s point total was its lowest since a 64-37 loss at ASU on Jan. 15, 2016. … CU has lost 53 consecutive road games against Associated Press Top 25 teams since a 62-51 upset at No. 20 Vanderbilt on Dec. 9, 2007. … Wetta had a career-high six turnovers. She had three consecutive turnover-free games before posting 10 in the two games this weekend. … Formann and Miller, CU’s top two 3-point shooters, went a combined 0-for-9 from 3-point range against Arizona and 3-for-23 in the two games this weekend.