Minneapolis >> Ty France singled in the 10th inning to give the Minnesota Twins a 4-3 victory Wednesday over the New York Mets, who had rallied with a three-run eighth.

With the speedy Byron Buxton conveniently on second as the automatic runner, France smacked a 1-1 pitch from Reed Garrett (0-1) with none out that bounced in center field with no chance for Tyrone Taylor to get his glove down.

Buxton, Harrison Bader and Willi Castro had RBI singles for the Twins (7-12), who won just their second series in six sets this season.

First base umpire Hunter Wendelstedt had to leave in the sixth after being hit in the head by a foul ball by Taylor.

Padres 4, Cubs 2 >> Fernando Tatis Jr. and Manny Machado each drove in two runs and Nick Pivetta pitched six strong innings for San Diego, who beat Chicago to take two of three in a series between National League division leaders.

The Padres improved to a major league-best 15-4. The NL West leaders have won 12 of 13 home games, with the lone loss coming on Tuesday night in 10 innings against Chicago.

The Central-leading Cubs (12-9) took two of three from the Padres at Wrigley Field earlier in the month.

Cardinals 4, Astros 1 >> Lars Nootbaar hit a three-run homer in the fifth inning, and Steven Matz pitched five strong innings in his first start of the season to help St. Louis beat Houston.

Matz (1-0) retired the last 15 batters he faced, striking out five, after allowing a run on a pair of singles to lead off the game.

Ryan Fernandez, Kyle Leahy and Phil Maton each pitched a scoreless inning of relief before Ryan Helsley pitched a scoreless ninth to earn his third save of the season.

Brewers 5, Tigers 1 >> Christian Yelich, Rhys Hoskins and Sal Frelick all hit home runs Wednesday and Milwaukee defeated Detroit.

Milwaukee took two of three in the series.

The Brewers pushed across a run in the second off Keider Montero (0-1) when Garrett Mitchell tripled with one out and scored on Oliver Dunn’s sacrifice bunt. Dunn became the first Brewers player to use a “torpedo” bat during the plate appearance.

Blue Jays 3, Braves 1 >> Vladimir Guerrero Jr. hit his first home run of the season and drove in a pair, Chris Bassitt pitched five shutout innings and Toronto spoiled Spencer Strider’s return from elbow surgery by beating Atlanta.

Chris Bassitt (2-0) struck out a season-high 10 and allowed three hits, all singles. The right-hander lowered his ERA to 0.77 through four starts.

The Blue Jays set a single-game, nine-inning record with 19 strikeouts.

Pirates 6, Nationals 1 >> Oneil Cruz hit his first career grand slam to help Bailey Falter and Pittsburgh beat Washington.

Henry Davis also connected for Pittsburgh, which had dropped four of five. Isiah Kiner-Falefa had two hits and scored run.

Falter (1-2) allowed two hits in seven scoreless innings. It was the 10th time this season that a Pirates starter went six innings or more — tops in the majors.

Orioles 9, Guardians 1 >> Jackson Holliday hit a second-inning grand slam, Dean Kremer turned in his best start of the young season and Baltimore routed Cleveland.

Holliday snapped an 0-for-17 drought with a drive that carried into the Baltimore bullpen in center field off Gavin Williams (1-1) with one out in the second.

Kremer (2-2) entered the game with an ERA of 8.16 but allowed just one run — a homer by Gabriel Arias in the third — in 5 1/3 innings. He allowed four hits.

Mariners 5, Reds 3 >> Cal Raleigh hit two more homers and Bryce Miller pitched five sharp innings, helping Seattle beat Cincinnati.

Raleigh hit a solo drive from each side of the plate. The catcher has five homers in his last five games, giving him 100 for his career.

Dylan Moore had two hits and scored two runs for the Mariners in their fifth win in six games. Randy Arozarena and J.P. Crawford each had two hits and drove in a run.

Diamondbacks 6, Marlins 2 >> Lourdes Gurriel Jr. hit a two-run homer and Arizona went deep four times to beat Miami for their fourth straight victory.

Josh Naylor, Pavin Smith and Tim Tawa added solo shots for the Diamondbacks, who have won six of seven following a three-game skid. They’ll go for a three-game sweep of the Marlins on Thursday afternoon.

Red Sox 1, Rays 0 >> David Hamilton hit a third-inning home run, four pitchers combined to strike out 13 and Boston beat Tampa Bay.

Hamilton lined a 3-2 fastball just inside the right-field foul pole off Rays starter Zack Littell (0-4) to lead off the third and give Boston all it needed in the three-game series finale. The Red Sox rebounded from Monday’s 16-1 loss to win the final two games.

Yankees 4, Royals 3 >> Aaron Judge hit a tiebreaking homer leading off the seventh inning that ended a 10-game drought, and New York defeated Kansas City to complete a three-game sweep.

With a runner at second base in the ninth, Cody Bellinger made a diving catch in right field on MJ Melendez’s sinking liner to preserve Fernando Cruz’s first career save.

A’s 3, White Sox 1 >> Gio Urshela snapped a sixth-inning tie with a two-run triple that sent the Athletics past struggling Chicago.

JJ Bleday had three hits, including a double and an RBI single, to help the Athletics win their second straight on a cold night.

Rangers 3, Angels 1 >> Corey Seager and Jake Burger each had three hits, and Texas beat Los Angeles.

Seager also drove in two runs in Texas’ seventh consecutive home win. It was Burger’s first multihit game with the Rangers.