TYRE, Lebanon >> Israeli jets struck multiple buildings in Lebanon’s southern coastal city of Tyre on Wednesday, sending up large clouds of black smoke, while Hezbollah confirmed that a top official widely expected to be the group’s next leader had been killed in an Israeli strike.

The state-run National News Agency reported that an Israeli strike on the nearby town of Maarakeh killed three people. There were no reports of casualties in Tyre, where the Israeli military had issued evacuation warnings prior to the strikes.

Hezbollah meanwhile fired another barrage of rockets into Israel, including two that set off air raid sirens in Tel Aviv before being intercepted. A cloud of smoke could be seen in the sky from the hotel where U.S. Secretary of State Antony Blinken was staying on his latest visit to the region to try to renew cease-fire talks.

On Wednesday night, the Israeli military said another four “projectiles” crossed from Lebanon into Israel, with two intercepted and one falling in open land. There were no immediate reports of any injuries, the military said.

Earlier Wednesday, Hezbollah confirmed that top official Hashem Safieddine had been killed in an announcement that came one day after Israel said it had killed him in a strike earlier this month in Beirut’s southern suburbs.

Safieddine, a powerful cleric within the party ranks, had been expected to succeed Hassan Nasrallah, one of the group’s founders, who was killed in an Israeli airstrike last month.

Hezbollah’s statement said Safieddine had “joined his brother, our most noble and precious martyr,” Nasrallah.

The group began firing rockets, missiles and drones into Israel, drawing retaliatory airstrikes, after Hamas’ Oct. 7, 2023 attack from Gaza triggered the war there. All-out war erupted in Lebanon last month, and Israeli strikes killed Nasrallah and most of his senior commanders. Israeli ground forces invaded southern Lebanon at the beginning of October.

Tyre, a provincial capital, had largely been spared in the Israel-Hezbollah war, but strikes in and around the city have intensified recently.

The 2,500-year-old city, about 50 miles south of Beirut, is known for its pristine beaches, ancient harbor and imposing Roman ruins and hippodrome, a UNESCO World Heritage Site. It is among Lebanon’s largest cities and a vibrant metropolis popular with tourists.

The buildings struck Wednesday were between several heritage sites, including the hippodrome and a cluster of seaside sites associated with the ancient Phoenicians and the Crusaders.

The Israeli military issued evacuation warnings a couple hours prior for dozens of buildings in the heart of the city. It told residents to move north of the Awali River, dozens of kilometers (miles) to the north.

Avichay Adraee, an Israeli military spokesman, said on the platform X that there were Hezbollah assets in the area of the evacuation warning, without elaborating or providing evidence.

The city is in southern Lebanon, where the Shiite Muslim Hezbollah has a strong presence, and its legislators are members of the group or its allies. But Tyre is also home to civilians with no ties to the group, including a sizable Christian community.

First responders from Lebanon’s Civil Defense warned residents through loudspeakers to evacuate and helped older adults and others who had difficulty leaving. Ali Safieddine, the head of the Civil Defense, told The Associated Press there were no casualties.

Dr. Wissam Ghazal, a health official in Tyre, said the strikes hit six buildings, flattening four of them, around 2 1/2 hours after the evacuation warnings. People displaced by the strikes could be seen in parks and sitting on the sides of nearby roads.

The head of Tyre’s disaster management unit, Mortada Mhanna, told the AP that although many people had fled, thousands of residents and others displaced from other areas have chosen to stay in the city. Many people, including hundreds of families, previously had fled villages in South Lebanon to seek refuge in shelters in Tyre.

An estimated 15,000 people remain in the city out of a pre-war population of about 100,000, Mhanna said.

“It’s very difficult for many to leave. They’re worried about being subjected to further chaos and displacement,” he said, adding that he and his team had chosen to stay in the city, but “it’s a big risk. It’s not safe here anymore.”

Lebanon’s Health Ministry said 28 people were killed and 139 wounded over the past 24 hours, raising the death toll since the conflict began last year to 2,574, with 12,001 people wounded. The fighting has driven 1.2 million people from their homes, including more than 400,000 children, according to the U.N. children’s agency.