Kentucky dragged another highly ranked opponent into the muck, and this time coach Mark Stoops and the Wildcats closed the deal.

Kentucky upset No. 6 Mississippi 20-17 on Saturday, when Rebels kicker Caden Davis hooked a 48-yard field-goal attempt way wide with 48 seconds left in the fourth quarter to give the Wildcats their highest-ranked win of Stoops’ 12-year career.

The Rebels (4-1, 0-1 Southeastern Conference) had a seven-game winning streak snapped and were shocked as a 15 1/2-point favorite according to BetMGM Sportsbook in their SEC opener.

The Wildcats (3-2, 1-2) took a three-point lead with 2:25 left in the fourth quarter, with a little fumble luck. Backup quarterback Gavin Wimsatt was heading toward the goal line with a keeper when an Ole Miss defender knocked the ball free — right to tight end Josh Kattus, who fell into the end zone.

AP Top 25

No. 1 Texas 35, Mississippi St. 13 >> Arch Manning passed for two touchdowns and ran for another score, and No. 1 Texas got another standout performance from its defense to earn the program’s first Southeastern Conference victory over Mississippi State.

Manning was 26-of-31 passing for 324 yards in his second consecutive start in place of Quinn Ewers, who is still recovering from a strained abdomen.

No. 16 Notre Dame 31, No. 15 Louisville 24 >> Riley Leonard threw two touchdown passes and ran for another, and No. 16 Notre Dame capitalized on No. 15 Louisville’s first three turnovers of the season.

Notre Dame (4-1) relied on a last-minute defensive stand to hand the Cardinals their first loss of the season. Louisville (3-1) had a delay-of-game penalty on a fourth-and-1 at the Notre Dame 46. After the five-yard penalty, an incomplete pass ended the Louisville comeback attempt.

No. 17 Clemson 40, Stanford 14 >> Clemson quarterback Cade Klubnik threw for four touchdowns and ran for another and the Tigers’ defense had three interceptions in a win over Stanford.

The victory for the 17th-ranked Tigers (3-1, 2-0 Atlantic Coast Conference) was the 173rd for coach Dabo Swinney, who tied the Florida State’s late national championship coach Bobby Bowden for most coaching victories with an ACC school.

No. 18 Iowa St. 20, Houston 0 >> Rocco Becht threw for 153 yards and a touchdown, Abu Sama III ran for 101 yards and a touchdown and No. 18 Iowa State beat Houston.

Iowa State (4-0, 1-0 Big 12) improved to 4-0 for the first time since 2000, with coach Matt Campbell becoming the school victory leader with 57. Houston (1-4, 0-2) fell to 1-4 for the first time since 2004.

No. 23 Kansas St. 42, No. 20 Oklahoma St. 20 >> Avery Johnson passed for three touchdowns and ran for two as No. 23 Kansas State routed No. 20 Oklahoma State.

No. 21 Oklahoma 27, Auburn 21 >> Kip Lewis returned an interception 61 yards for the game-winning touchdown, and No. 21 Oklahoma rallied from an 11-point fourth-quarter deficit to defeat Auburn for its first-ever Southeastern Conference win.

No. 22 BYU 34, Baylor 28 >> BYU safety Crew Wakley’s leaping interception, near midfield right in front of the Baylor bench with 59 seconds left, finally clinched a victory. The Cougars never trailed but had to hold on after twice building three-touchdown leads before halftime when Jake Retzlaff threw for two scores and ran for another one.

No. 24 Texas A&M 21, Arkansas 17 >> Marcel Reed threw for two touchdowns and ran for a score, and No. 24 Texas A&M beat Arkansas in their final scheduled neutral-site meeting at the home of the Dallas Cowboys.

Big 10

No. 3 Ohio St. 38, Michigan St. 7 >> Jeremiah Smith had a 19-yard touchdown run and made a one-handed, 17-yard catch for a score in the second quarter, helping No. 3 Ohio State pull away and rout Michigan State 38-7 Saturday night.

Smith’s speed allowed him to go untouched on an end-around midway through the second quarter. His skill set him up to leap and snag Devin Brown’s pass with his right hand — three plays after needing only one hand to make a 27-yard catch — to put Ohio State ahead 24-7 in the final minute of the first half.

No. 13 Southern Cal 38, Wisconsin 21 >> Miller Moss threw two of his three touchdown passes to Ja’Kobi Lane, and No. 13 Southern California rallied from an 11-point deficit in the second half to beat Wisconsin in the Trojans’ first Big Ten home game.

One week after narrowly losing its Big Ten debut at Michigan, USC trailed 21-10 at halftime and received a few boos from its home crowd after committing three turnovers in the first half. The Trojans (3-1, 1-1) responded superbly, outscoring Wisconsin 28-0 in the second half of their school’s first Big Ten victory.

Indiana 42, Maryland 28 >> Kurtis Rourke threw for a season-high 359 yards and three touchdowns, and the Indiana defense came up with stop after stop over the final 22 minutes as Indiana defeated Maryland for its first 5-0 start since 1967.

Despite committing four turnovers — their first four all season — the defense allowed just one TD over the final 22 minutes and Rourke rebounded from two first-half interceptions to help Indiana top the 30-point for the fifth straight game, their longest streak since 2000.

They’ve opened the season with five consecutive wins for just the third time in school history.

Nebraska 28, Purdue 10 >> Dylan Raiola threw for 257 yards and a touchdown to lead Nebraska to a victory over Purdue.

After playing a scoreless first half and trailing 3-0 late in the third quarter, the Cornhuskers scored 28 unanswered points and kept Purdue out of the end zone until the Boilermakers scored in the final 2 minutes.