Saquon Barkley rushed for 167 yards to top 2,000 on the season, backup quarterback Kenny Pickett ran and threw for touchdowns before departing with injured ribs, and the Philadelphia Eagles clinched the NFC East title by routing the visiting Dallas Cowboys 41-7 on Sunday.

Barkley has 2,005 yards and needs 101 in next week’s mostly meaningless regular-season finale to top Eric Dickerson and his 2,105 yards for the Rams in 1984.

The Eagles (13-3) led 24-7 in the third quarter when Pickett was drilled by defensive end Micah Parsons, ending his first start in place of the concussed Jalen Hurts. Tanner McKee, a third-stringer out of Stanford, entered the game and the Eagles finished the drive with a field goal.

McKee later threw two TD passes, a 20-yarder to A.J. Brown and a 25-yarder to DeVonta Smith.

Barkley had 31 carries and his last one went for 23 yards to push him over 2,000.

BUCCANEERS 48, PANTHERS 14: Baker Mayfield threw for 359 yards and five touchdowns to help Tampa Bay keep its division and playoff hopes alive with a home rout of Carolina.

It was the fifth win in the past six weeks for the Bucs (9-7).

Mayfield threw TD passes of 2 and 1 yards to Mike Evans, and Tampa Bay produced points on five straight first-half possessions to build a 27-7 lead. Jalen McMillan scored on receptions of 10 and 16 yards, linebacker J.J. Russell returned a blocked punt for a third-quarter TD and rookie Bucky Irving had 120 yards rushing on 20 carries and four receptions for 77 yards.

Irving went over 1,000 yards for the season (1,033) despite primarily being used as a backup to Rachaad White.

GIANTS 45, COLTS 33: New York snapped a franchise-record 10-game losing streak and ended Indianapolis’ slim playoff hopes as Drew Lock threw four touchdown passes and ran for another score in the Giants’ first home win of the season.

Lock sandwiched touchdown passes of 31 and 59 yards to Malik Nabers around TD passes of 32 yards to Darius Slayton and 5 yards to Wan’Dale Robinson in leading the Giants (3-13) to their first win since beating Seattle on Oct. 6.

New York’s Ihmir Smith-Marsette had a 100-yard return on the second-half kickoff.

Jonathan Taylor scored on runs of 3 and 26 yards for Indianapolis (7-9), while Joe Flacco, subbing for the injured Anthony Richardson, threw touchdown passes of 13 yards to Alec Pierce and 7 yards to Michael Pittman.

RAIDERS 25, SAINTS 10: Aidan O’Connell passed for two touchdowns and Las Vegas won at New Orleans (5-11).

O’Connell finished with 242 yards passing, including a 3-yard TD pass to Jakobi Meyers and an 18-yarder to Tre Tucker.

Daniel Carlson kicked four field goals for the Raiders (4-12).

JAGUARS 20, TITANS 13: Mac Jones threw two touchdown passes, including one to standout rookie Brian Thomas Jr., and Jacksonville (4-12) beat visiting Tennessee (3-13).

Thomas, the first-round draft pick from LSU, finished with seven receptions for 91 yards.

DOLPHINS 20, BROWNS 3: Tyler Huntley scrambled for a touchdown and threw for one while starting for Tua Tagovailoa, and visiting Miami stayed in the playoff race with a win over Cleveland (3-13).

With Tagovailoa sidelined by a hip injury, Huntley did enough to keep the Dolphins (8-8) alive.