San Francisco >> Much has changed since the Warriors came into Boston and beat the defending champions in their own arena on Nov. 6.

De’Anthony Melton tore his ACL and got replaced by Dennis Schroder. Jonathan Kuminga rose, then fell to a significant ankle sprain. The win was part of a 12-3 start, and since the Warriors became the first team ever to open a season that hot and dip below .500 at any point thereafter. News cycles swirled around the existential questions engulfing this iteration of a dynastic era.

The Celtics haven’t even been playing well of late, going through the typical post-championship malaise. They still showed how much juice the Warriors have lost in the past couple months.The Celtics shut down Golden State’s fledgling, short-handed offense in a commanding 125-85 victory over the Warriors at Chase Center. Boston had its championship starting-five while Golden State was missing Draymond Green, Kuminga and Brandin Podziemski. The extreme talent disparity was apparent, as the Warriors trailed by as much as 45 and didn’t own a lead after the first quarter.

Golden State (21-21) scored a season-low 85 points in their second largest margin of defeat this year. They shot 34.8% from the floor and 26.4% from deep, numbers made to look better than they were by garbage time.

The Warriors have insisted they’re not waving the white flag on the season, even if their activity leading up to the Feb. 6 trade deadline is as quiet as they’ve forecasted. But in this beaten and battered state, simply competing against competent teams is going to be difficult.

The absence of Green — out at least the next week with a mild left calf strain — along with Jonathan Kuminga’s sprained ankle opened the door for Moses Moody (13 points, five rebounds, five assists) to play more power forward. It’s where the Warriors have liked Moody best for years, Steve Kerr said, because of his switchability defensively and floor-spacing.

In Moody’s first minutes, he stood up Kristaps Porzingis in the post despite giving up eight inches of height. Then he drove down the lane and found Kevon Looney for an assist.

The defensive stop was notable. The Warriors appeared to switch on defense more than usual, likely because of Green’s injury. That left mismatches for the Celtics to pick at.

Boston targeted switches, either against Steph Curry or with a guard sizing up Trayce Jackson-Davis on the perimeter. While that strategy makes sense, it may have taken Boston out of its go-to offense at times.

But as Golden State’s defense held up, its offense didn’t reward it.

That Looney jumper was the only Warriors field goal in the last 5:20 of the first quarter. Curry sat, and the bench unit burped up 10-1 Celtics run. Buddy Hield, who went 1-for-3 at the foul line, was particularly ineffective in that key stretch.

Golden State went 7:32 of game time without a made field goal. They missed 14 of their first 15 3-point attempts, including several clean looks.

A Dennis Schroder 3 gave the Warriors eight points in 11 game minutes. Even a miniature Curry flurry at the end of the half didn’t do much as the Warriors went 3-for-24 (12.5%) from behind the arc in the first half and fell behind by 15.

One of the worst offenses in the league for almost two months now, the Warriors scored just 39 first-half points. Andrew Wiggins missed his first seven field goal attempts after a few high-volume scoring games.