The papal thriller “Conclave” won best ensemble and Timothée Chalamet took best actor at the 31st Screen Actors Guild Awards on Sunday, a pair of twists that added a few final wrinkles to an unusually unpredictable awards season.

In winning the guild’s top award, Edward Berger’s Vatican-set drama triumphed just as the Catholic Church was praying for the health of Pope Francis, who remained in critical condition Sunday after an asthmatic respiratory crisis. “Conclave” dramatizes the fictional election of a new pope. Earlier in the evening onstage, Isabella Rossellini shared the cast’s best wishes for Pope Francis.

All the momentum going into the SAG Awards was with Sean Baker’s “Anora,” which had won with the producers, directors and writers guilds. Now, with “Conclave” winning with the actors and at the BAFTAs, what will nab best picture in a week’s time at the Academy Awards is, again, anyone’s guess.

“Wow,” said “Conclave” star Ralph Fiennes taking the stage. “I’ve not been elected to speak. I’ve been designated to speak on behalf of our conclave, our ensemble.”

That wasn’t the only surprise in the ceremony held at the Shrine Auditorium in Los Angeles and streamed lived by Netflix. Chalamet’s best actor win upset “The Brutalist” star Adrien Brody and put the 29-year-old on course to possibly win his first Academy Award.

Chalamet looked visibly surprised when his name was announced at the ceremony. But once he reached the staged, the “A Complete Unknown” star spoke with composure and confidence.

“The truth is, this was 5½ years of my life,” said Chalamet. “I poured everything I had into playing this incomparable artist, Mr. Bob Dylan, a true American hero. It was the honor of a lifetime playing him.”

He then added: “The truth is, I’m really in pursuit of greatness. I know people don’t usually talk like that, but I want to be one of the greats.”

The other Oscar favorites — Demi Moore, Zoe Saldaña and Kieran Culkin — all won. The SAG Awards are closely watched as an Oscar preview. Their picks don’t always align exactly with those of the film academy, but they often nearly do.

The last three best ensemble winners — “Oppenheimer,” “Everything Everywhere All at Once” and “CODA” — all went on to win best picture at the Oscars. All but one of the SAG acting winners of the last three years has also won the Oscar.

Moore seemingly solidified her Oscar chances by following up her Golden Globe win for her performance in “The Substance.” Moore, whose campaign was boosted by her speech about being pigeonholed a “popcorn actress,” has traded awards with “Anora” breakthrough Mikey Madison.

“What we believe is so much more powerful than what we think,” said Moore. “The saying, ‘I’ll believe it when I see it’ — the reality is when I believe it, I will see it.”

The SAG Awards unfolded against the backdrop of the aftermath of the devastating wildfires that began in early January. Those fires forced the guild to cancel its in-person nominations announcement and launch a disaster relief fund for SAG-AFTRA members affected. Host Kristen Bell introduced attending firefighters as “the most attractive tables” among a sea of stars.

Jane Fonda, 87, given the guild’s Life Achievement Award, provided the evening with its most passionately political moment. Fonda, a famed activist, spoke indirectly about President Donald Trump’s administration.

“We are in our documentary moment,” said Fonda. “This is it. And it’s not a rehearsal.”

Fonda added that “woke just means you give a damn about other people.”

“A whole lot of people are going to be hurt by what’s happening, by what’s coming our way,” said Fonda. “We are going to need a big tent to resist what’s coming at us.”

Jean Smart, who had advocated for canceling award shows because of the wildfires, won best female actor in a comedy series for “Hacks.” Smart didn’t attend, but participated in a pre-taped introduction as her character, Deborah Vance.

Also not in attendance: Martin Short, although he upset Jeremy Allen White to win best male actor in a comedy series for “Only Murders in the Building.” The Hulu series also won for best comedy ensemble.

“Wait, we never win. This is so weird,” said Selena Gomez. “Marty and Steve (Martin) aren’t here because, you know, they don’t really care.”

Colin Farrell won his first SAG award, for his performance in “The Penguin.”