“Parasite” filmmaker Bong Joon Ho’s original science fiction film “Mickey 17” opened in first place on the North American box office charts.

According to studio estimates Sunday, the Robert Pattinson-led film earned $19.1 million in its first weekend in theaters, which was enough to dethrone “Captain America: Brave New World” after a three-week reign.

Overseas, “Mickey 17” has already made $34.2 million, bringing its worldwide total to $53.3 million.

But profitability for the film is a long way off: It cost a reported $118 million to produce, which does not account for millions spent on marketing and promotion.

A week following the Oscars, where “Anora” filmmakerSean Baker made an impassioned speech about the importance of the theatrical experience — for filmmakers to keep making movies for the big screens, for distributors to focus on theatrical releases and for audiences to keep going — “Mickey 17” is perhaps the perfect representation of this moment in the business, or at least an interesting case study.

It’s an original film from an Oscar-winning director led by a big star that was afforded a blockbuster budget and given a robust theatrical release by Warner Bros., one of the few major studios remaining.

Based on the novel “Mickey7” by Edward Ashton, Pattinson plays an expendable employee who dies on missions and is reprinted time and time again. Steven Yeun, Naomi Ackie, Toni Collette and Mark Ruffalo also star.

Second place went to “Captain America: Brave New World,” which added $8.5 million from 3,480 locations in North America and $9.2 million internationally. Its global total currently rests at $370.8 million.

Holdovers “Last Breath,” “The Monkey” and “Paddington in Peru” rounded out the top five.

The weekend also had several other newcomers in “In the Lost Lands,” a fantasy film from Paul W.S. Anderson starring Milla Jovovich and Dave Bautista, and Angel Studios’ “Rule Breakers,” about Afghani girls on a robotics team.