James Wood homered twice and matched a career high with five RBIs, leading the Washington Nationals over the Dodgers 8-2 on Tuesday night for their fourth consecutive victory and their first home series win over Los Angeles since 2014.

Los Angeles has lost four of five following an 8-0 start. Shohei Ohtani was 1 for 5 with a ninth-inning single.

Wood hit a two-run homer off Justin Wrobleski (0-1) in the first, drew a bases-loaded walk in a three-run second inning and hit another two-run shot in the fourth for an 8-0 lead.

Wood also went deep in Monday’s series opener.

Wrobleski started in place of two-time Cy Young Award winner Blake Snell, who went on the injured list Sunday with shoulder inflammation. Wrobleski allowed eight runs in five innings.

Mets 10, Marlins 5 >> Pete Alonso drove in four runs, Francisco Lindor hit a leadoff homer and New York beat visiting Miami for its sixth consecutive victory.

Clay Holmes (1-1) struck out a career-high 10 in 5 1/3 innings for his first win with the Mets and second as a major league starter.

Brandon Nimmo broke a fifth-inning tie with a two-run double, and Starling Marte blooped a two-run single.

Alonso laced a three-run double to left-center off Ronny Henriquez in the sixth.

Cardinals 5, Pirates 3 >> Pittsburgh ace Paul Skenes was knocked around by St. Louis, allowing a career-high five runs in a home loss.

Skenes (1-1), who was electric in his first two starts this season, was spotty this time around. The 22-year-old reigning National League Rookie of the Year allowed six hits with a walk and seven strikeouts as his ERA more than doubled from 1.46 to 3.44.

Victor Scott II had two hits, including a two-run triple off Skenes in the third.

Sonny Gray (2-0) breezed through five innings for St. Louis, surrendering just one run and three hits.

Tigers 5, Yankees 0 >> Tarik Skubal allowed four hits over six innings, Spencer Torkelson hit the first of three homers in the fourth off Carlos Carrasco and Detroit extended its winning streak to five, beating visiting New York.

Skubal (1-2), the reigning AL Cy Young Award winner, struck out six and walked none, lowering his ERA from 5.91 to 3.78. He allowed singles to Paul Goldschmidt and Ben Rice starting the game, then retired 16 straight batters.

New York has lost three straight.

Guardians 1, White Sox 0 >> Nolan Jones drew a bases-loaded walk from Mike Clevinger in the ninth and Cleveland won its home opener over Chicago, which lost its sixth in a row.

Blue Jays 6, Red Sox 1 >> George Springer homered and Easton Lucas pitched 5 1/3 scoreless innings to lead Toronto to a victory over Boston at Fenway Park.

Garrett Crochet (1-1) gave up four runs — just one earned — on five hits and four walks while striking out five in 5 2/3 innings.