President Donald Trump has expressed irritation over Ireland’s role as a major exporter of drugs to the U.S. Botox users may soon learn how angry he was.

Trump was expected to announce wide-ranging tariffs at the White House on Wednesday designed to bring manufacturing and jobs back to the U.S. While sector-specific levies on pharmaceuticals aren’t expected yet, it is likely the president will put reciprocal tariffs on specific countries — and Ireland is viewed as a key target.

Tariffs are widely expected to drive up the prices of goods across the board, but Americans don’t typically pay the full price for their pharmaceuticals directly. Instead, they pay a copay or portion of the cost set by their prescription drug plans.

AbbVie Inc.’s anti-wrinkle injection, Botox, is different. It’s one of the rare cash-pay drugs when it’s used to smooth out forehead wrinkles. (When it’s used to treat medical conditions, it typically goes through insurance.) Because of the cash-pay nature of the aesthetics business, consumer demand for Botox waxes and wanes with economic cycles.

AbbVie, in part, makes Botox at a secure plant in Ireland. That could make moving production back to the U.S. more of a challenge if Trump goes through with levies on the country.

Botox is made from one of the most toxic substances on Earth, botulinum toxin, and its purified medical recipe is a closely guarded secret. The toxin is so powerful that a tiny amount can suffocate a person by paralyzing muscles used for breathing. It is considered one of the world’s most deadly potential agents of bioterrorism. Because of this, if even a speck of the toxin goes missing, it must be reported to the U.S. Centers for Disease Control and Prevention.

AbbVie does not publicly discuss its suppliers or disclose where products are manufactured, a spokesperson said in a statement.

“To serve our patients and customers around the world, AbbVie maintains a robust, diversified, and redundant manufacturing network with geographic balance and multiple supply sites,” the spokesperson said.

It’s not yet clear how tariffs will impact drugmakers like AbbVie. However, if Trump does go through with levies on Ireland, the company will likely have to eat the costs, or raise prices for its wildly popular drug, which can cost anywhere from $200 to $600 to get rid of forehead lines.