KANSAS CITY, Mo. — Patrick Mahomes threw for 260 yards and a touchdown while running for a score on his ailing ankle, and the Chiefs took a big step toward securing the No. 1 seed in the AFC playoffs with a 27-19 victory over the Texans on Saturday.

The AFC West champion Chiefs (14-1), who have won four straight against the AFC South champ Texans (9-6), can clinch the postseason bye if the Bills lose to or tie the Patriots on Sunday. If the Bills win, the Chiefs can wrap it up by beating the Steelers on Christmas Day.

Xavier Worthy had seven catches for 65 yards and a touchdown, Kareem Hunt ran for 55 yards and another score, and Marquise Brown had five catches for 45 yards for the Chiefs in his first game this season after recovering from a shoulder injury.

C.J. Stroud had 244 yards and two touchdown passes with two interceptions for the Texans, though one of those TD throws came at great expense. Tank Dell, who had six catches for 98 yards, hurt his left knee on the play and was carted from the field.

Dalton Schultz also had a TD reception for the Texans. Joe Mixon was held to 57 yards rushing.

There were questions early in the week about whether Mahomes would play after sustaining a high ankle sprain late in last week’s win over the Browns. But the two-time MVP was off the injury report by Friday, and Mahomes showed no problems on the Chiefs’ opening drive Saturday, finishing it off with a 15-yard scramble to the end zone.

It was merely the start of a back-and-forth first half.

The Texans answered with a 33-yard field goal, then went on a 13-play, 82-yard drive that ended with Stroud’s touchdown toss to Schutlz. But the Chiefs quickly regained the lead when Hunt barreled into the end zone, and they tacked on a field goal after Stroud’s second interception to lead 17-10 at the break.

Dell was hurt on the Texans’ opening drive of the third quarter. He came across the back of the end zone and made a spectacular catch but collided with teammate Jared Wayne on his way to the ground.

Stroud was visibly shaken as Dell, holding his hands to his facemask, was driven off the field and up the tunnel in the corner of Arrowhead Stadium. The Texans quarterback had to be consoled by teammates when he returned to the sideline. Dell was the second Texans player to be carted off during a game full of injuries. Free safety Jimmie Ward also was taken away on a cart after hurting his foot late in the first half.

Ka’imi Fairbairn promptly missed the extra point, and any momentum the Texans might’ve disappeared.

The Chiefs marched the other way, relying heavily on Worthy, who touched the ball four times on the drive. He finished it off with an 8-yard reception, giving the first-round a season-high for receiving yards and his eighth touchdown. The teams matched fourth-quarter field goals, and the Texans took over trailing 27-19 with just over five minutes to go.

They promptly went three-and-out and the Chiefs ran out the clock from there.