Tech and life sciences companies have slashed hundreds more Bay Area jobs, marking a fresh round of employment setbacks for the vital sectors.

Bio-Rad Laboratories, Corning Optical Communications, Zendesk and Exabeam are among the latest companies to disclose their decisions to eliminate positions in the region. In total, 305 workers are affected, according to official notices on file with the state Employment Development Department.

Here are some details of the latest cutbacks, which were all described as permanent:

• Bio-Rad Laboratories, a life sciences and tech company, disclosed 131 job cuts affecting workers in Hercules, Pleasanton and Richmond. Most of the cuts occurred at its headquarters in Hercules, where 113 jobs were lost. The staffing reductions were slated to occur on April 15.

• Corning Optical Communications, a provider of fiber-optics communications equipment, revealed 80 layoffs in Milpitas. The layoffs occurred on Feb. 20. The affected job site is being permanently closed.

• Zendesk, a software company, reported 51 staffing reductions in San Francisco. The cutbacks are scheduled for April 21.

• Exabeam, an information security firm, disclosed 43 layoffs in Foster City. The downsizing took place Feb. 4.

Ongoing tech, biotech and life sciences layoffs have hobbled the Bay Area’s ability to add jobs.

In 2024, the Bay Area added 7,600 jobs, which was an increase of 0.2% from the totals of a year before in the region.

That was one of the weakest increases among urban centers statewide last year. The small rise in the Bay Area job market also was far below the 1% increase for California in 2024, this news organization’s analysis of EDD figures shows.