Brock Purdy is fine, but when the 49ers take the practice field Thursday in preparation for the Carolina Panthers in Week 12, they’ll have a new place kicker and a different player at middle linebacker for the third time this season.

Purdy, who missed the previous six games with right turf toe, showed little signs of rust and got through a 41-22 road win over the Arizona Cardinals Sunday without re-injury, unlike his previous start on Sept. 28 against Jacksonville.

Place kicker Eddy Piñeiro and middle linebacker Tatum Bethune weren’t as fortunate. Piñeiro sustained a Grade 1 right hamstring strain and will miss an undetermined amount of time. The 49ers will hold tryouts for place kickers today and/or Wednesday.

“We’re going to bring in some guys for a workout,” coach Kyle Shanahan said Monday in a conference call with local media. “They’re working on that now.”A Grade 1 strain is a mild overstretching of muscle fibers. Shanahan termed Piñeiro’s timeline as “week to week.”

Piñeiro has made all 22 of his field goal attempts since taking over for Jake Moody in Week 2. Strangely, he has failed four of 22 extra point attempts, two of which were blocked. He had a miss and a block against Arizona.

Shanahan compared the comfort level with Piñeiro to that of Robbie Gould, who was 72-for-75 over the 2017-18 seasons on field goal attempts and never missed one in the postseason with the 49ers.

“Eddy’s given that same feeling and he’s been awesome so far,” Shanahan said. “We’re pumped up to get him on the Niners.”

Bethune was done atter 24 snaps with a high ankle sprain and although he probably isn’t headed for injured reserve, veteran Curtis Robinson will assume the role that first belonged to Fred Warner and then Bethune. Bethune started the last five games after Warner was lost for the season with a broken ankle and his 67 tackles are second on the 49ers to Dee Winters’ 77.

Robinson, 27, was lost to a torn ACL last season. He played a career high 54 snaps against Arizona plus his usual special teams load (13 snaps) and led the 49ers with 11 tackles.

“I thought he did a real good job,” Shanahan said. “Curtis has been preparing for that opportunity for awhile, especially coming back from that ACL. He did a hell of a job.”

Another potential “mike” linebacker, Jalen Graham, is on the practice squad, and the 49ers could add another to the practice squad if he’s promoted.

Purdy, who was 19 of 26 for 200 yards and three touchdowns, had one awkward moment that seemed to put his right toe at risk when he was tackled from behind while running to his right, but Shanahan said he was never concerned.

“I never did have that feeling throughout the game,” Shanahan said. “He gave us a ton of confidence last week with how he’s looked in practice.”

The 49ers will not open up the practice window for wide receiver Brandon Aiyuk (ACL, MCL rehab). Wide receiver/return specialist Jacob Cowing (hamstring) probably won’t be practicing until after the 49ers’ bye week (the weekend of Dec. 7).

“Brandon is week to week,” Shanahan said. “With a big injury like that, just waiting until he’s fully comfortable to start practicing.”

Despite the gaudy passing numbers put up by Jacoby Brissett of Arizona (47-for-57, 452 yards, two touchdowns), Shanahan felt good about the 49ers’ defensive performance. Malik Mustapha and Deommodore Lenoir had interceptions that directly led to 10 points.

Tight end George Kittle said he is zeroing in on new players to watch on defense since the loss of his favorites, Nick Bosa and Fred Warner.

One of them is rookie defensive Alfred Collins, who Kittle first mistakenly identified as “Alfred Morris” a former running back who spent the 2018 season with the 49ers and gained 428 yards.

“Alfred has stood out for me because of his constant effort, no matter where the ball is, he’s chasing it down, and I really appreciate that from a young player,” Kittle said.