No. 1 Ohio State 38, Penn State 14 >> Julian Sayin passed for 316 yards and four touchdowns, Jeremiah Smith scored twice and top-ranked Ohio State pulled away in the second half to defeat Penn State.
The Buckeyes (8-0, 5-0 Big Ten) had a 17-14 lead at halftime, but took control in the second half, scoring on three of their first four possessions.
Kaytron Allen and Nicholas Singleton both had rushing scores for Penn State (3-5, 0-5), which has dropped five straight and lost both games with interim coach Terry Smith at the helm. Smith took over after James Franklin was fired on Oct. 12.
No. 2 Indiana 55, Maryland 10 >> Fernando Mendoza threw for a touchdown and ran for one, and No. 2 Indiana remained undefeated with a rout of Maryland.
Mendoza recovered from an early interception, and he also had to play most of the game without his top target. Star receiver Elijah Sarratt left in the first quarter with hamstring tightness, ending his nation-leading streak of 46 consecutive games with a catch.
Still, this was another one-sided game for the Hoosiers (9-0, 6-0 Big Ten), who since winning at Oregon have added victories over Michigan State, UCLA and Maryland by a combined 120 points.
No. 5 Georgia 24, Florida 20 >> Gunner Stockton threw two touchdown passes, Chauncey Bowens scored on a late 36-yard run and No. 5 Georgia escaped the rivalry known as the “World’s Largest Outdoor Cocktail Party” with a victory against Florida.
It was the Bulldogs’ fifth consecutive victory in the series and their eighth in the last nine meetings.
No. 7 Ole Miss 30, South Carolina 14 >> Mississippi sacked LaNorris Sellers six times and the No. 7 Rebels held off upset-minded South Carolina.
Ole Miss, third in the SEC and ninth nationally in total offense, looked rather pedestrian as Trinidad Chambliss completed just 12 of 21 passes with a touchdown and an interception.
N.C. State 48, NO. 8 Georgia Tech 36 >> Duke Scott ran for a career-best 196 yards in place of injured Atlantic Coast Conference rushing leader Hollywood Smothers to help N.C. State stun No. 8 Georgia Tech, ending the Yellow Jackets’ unbeaten run.
Scott broke loose around the left side for a 30-yard TD with 4:07 left to effectively seal this one. The redshirt freshman ran tough all night and having home fans roaring “Duuuuuuuke!” after several of his gains.
No. 12 Notre Dame 25, Boston College 10 >> Jeremiyah Love broke free for a 94-yard touchdown run on the first play after a Notre Dame interception squelched a potential game-tying drive and the 12th-ranked Fighting Irish won their sixth straight, beating Boston College.
No. 13 Texas Tech 43, Kansas State 20 >> Berhen Morton threw for 249 yards and two touchdowns in his return from an injury, J’Koby Williams ran for 135 yards and a score, and No. 13 Texas Tech romped Kansas State.
No. 15 Virginia 31, California 21 >> J’Mari Taylor ran for two touchdowns and No. 15 Virginia extended its winning streak to seven straight games for the first time since 2007 by beating California.
No. 16 Louisville 28, Virginia Tech 16 >> Isaac Brown rushed for 130 yards and a touchdown before leaving late with a leg injury and Keyjuan Brown scored twice in the second half to lift No. 16 Louisville to a victory over Virginia Tech.
No. 21 Michigan 21, PURDUE 16 >> Jordan Marshall had career highs with 185 yards rushing and three touchdowns, helping No. 21 Michigan hold off Purdue.
No. 23 USC 21, Nebraska 17 >> King Miller ran for 129 yards and the go-ahead touchdown in the fourth quarter and No. 23 USC overcame its worst passing performance in seven years to beat Nebraska.
—The Associated Press
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