U.S. regulators on Wednesday banned the dye called Red 3 from the nation’s food supply, nearly 35 years after it was barred from cosmetics because of potential cancer risk.

Food and Drug Administration officials granted a 2022 petition filed by two dozen food safety and health advocates, who urged the agency to revoke authorization for the substance that gives some candies, snack cakes and maraschino cherries a bright red hue.

The agency said it was taking the action as a “matter of law” because some studies have found that the dye caused cancer in lab rats. Officials cited a statute known as the Delaney Clause, which requires the FDA to ban any additive found to cause cancer in people or animals.

California in 2023 banned Red Dye 3 and several other ingredients from its food supply, beginning in 2027.

The dye is known as erythrosine, FD&C Red No. 3 or Red 3. The ban removes it from the list of approved color additives in foods, dietary supplements and oral medicines, such as cough syrups. More than three decades ago, the FDA declined to authorize the use of Red 3 in cosmetics and externally applied drugs because a study showed it caused cancer when eaten by rats.

“The FDA is taking action that will remove the authorization for the use of FD&C Red No. 3 in food and ingested drugs,” said Jim Jones, the FDA’s deputy commissioner for human foods. “Evidence shows cancer in laboratory male rats exposed to high levels of FD&C Red No.3. Importantly, the way that FD&C Red No. 3 causes cancer in male rats does not occur in humans.”

As in California, food manufacturers will have until January 2027 to remove the dye from their products, while makers of ingested drugs have until January 2028 to do the same. Other countries still allow for certain uses of the dye, but imported foods must meet the new U.S. requirement.

Consumer advocates praised the decision.

“This is a welcome, but long overdue, action from the FDA: removing the unsustainable double standard in which Red 3 was banned from lipstick but permitted in candy,” said Dr. Peter Lurie, director of the group Center for Science in the Public Interest, which led the petition effort.

It’s not clear whether the ban will face legal challenges from food manufacturers because evidence hasn’t determined that the dye causes cancer when consumed by humans. About two-thirds of Americans favor restricting or reformulating processed foods to remove ingredients like added sugar or dyes, according to a new AP-NORC poll. Support is particularly high among U.S. adults with a college degree, as well as those with a higher household income. About 8 in 10 people with a college degree favor restricting or reformulating processed foods, compared with about 6 in 10 people without a college degree, the poll showed.

Red 3 is banned for food use in Europe, Australia and New Zealand except in certain kinds of cherries.