DEIR AL-BALAH, Gaza Strip >> Israeli aircraft struck a residential block in war-ravaged northern Gaza on Wednesday, killing at least 23 people, health officials said, as the renewed fighting in the devastated Palestinian enclave showed no signs of slowing.

The Al-Ahly hospital said at least 23 people were killed in the strike, including eight women and eight children. The territory’s Health Ministry confirmed the figures.

The strike hit a four-story building in the Shijaiyah neighborhood of Gaza City, and rescue teams were searching for victims under the rubble, according to the Health Ministry’s emergency service. The civil defense, a rescue group that operates under the Hamas-run government, said other neighboring buildings were damaged in the strike.

The Israeli military said it struck a senior Hamas fighter who it said was behind attacks emanating from Shijaiyah, but it didn’t name him or provide further details. Israel blames the deaths of Palestinian civilians on the fighter group, because it embeds itself in dense urban areas.

As it ratchets up pressure on Hamas to agree to free hostages, Israel has issued sweeping evacuation orders for parts of Gaza, including Shijaiyah. It imposed a blockade on food, fuel and humanitarian aid that has left civilians facing acute shortages as supplies dwindle. It has pledged to seize large parts of the Palestinian territory and establish a new security corridor through it.

The U.N. said the Israeli military has denied aid workers permission for more than two-thirds of 170 attempts to move humanitarian supplies within the Gaza Strip since the ceasefire ended. U.N. spokesperson Stephane Dujarric said efforts to get dwindling aid supplies to Palestinians were “severely strained.”

The Israeli military did not immediately comment.

Earlier this week, Hamas fired its strongest volley of rockets since the ceasefire collapsed, lobbing 10 projectiles toward southern Israel.

Israel resumed its war against Hamas in Gaza last month after an eight-week ceasefire collapsed. The ceasefire brought a much-needed reprieve from the fighting to war-weary Palestinians in Gaza and sent an infusion of humanitarian aid to the territory. It also led to the release of 25 living Israeli hostages held in Gaza and the return of the remains of eight others, in exchange for hundreds of Palestinian prisoners.

Mediators have since attempted to bring the sides to a bridging agreement that would again pause the war, free hostages and open the door for talks on the war’s end, something Israeli Prime Minister Benjamin Netanyahu said he won’t agree to until Hamas is defeated. Hamas wants the war to end before it frees the remaining 59 hostages it holds, 24 of whom are believed to be alive.

The war, which was sparked by Hamas’ Oct. 7, 2023, attacks on southern Israel, has seen the deadliest fighting between Israelis and Palestinians in their history. It has ignited a humanitarian crisis in already impoverished Gaza, and has sent shockwaves across the region and beyond.