Here’s my best bets for Week 4:

NEW ORLEANS AT ATLANTA

Obvious starters: Alvin Kamara (NO), Chris Olave (NO), Bijan Robinson (ATL), Drake London (ATL), Kyle Pitts (ATL).

Who to start: Derek Carr (NO) remains in the streaming conversation against a defense allowing the 10th-most fantasy points to opposing quarterbacks. Darnell Mooney (ATL) maintains flex appeal as the overall WR34 in standard formats (WR35 in PPR) though three weeks.

Who to sit: Rashid Shaheed (NO) remains a boom-or-bust option after failing to catch one of his five targets against the Eagles. Taysom Hill (NO) remains the quintessential boom-or-bust option with only 10 touches in his two games this season. Juwan Johnson (NO) hasn’t seen a target since Week 1.

L.A. RAMS AT CHICAGO

Obvious starters: Kyren Williams (LAR), DJ Moore (CHI).

Who to start: Tutu Atwell (LAR) appears to be Stafford’s top target with Cooper Kupp and Puka Nacua sidelined, producing seven receptions for 141 yards on nine targets the last two games. Keenan Allen (CHI) maintains WR3/flex upside if he’s active (heel). D’Andre Swift (CHI) maintains flex appeal despite the terrible start with double-digit touches in every game this season and a positive matchup. Rome Odunze (CHI) has flex appeal against a defense allowing the second-most fantasy points to wide receivers. Cole Kmet (CHI) faces a defense allowing the fourth-most fantasy points to tight ends.

Who to sit: I’m fading Matthew Stafford (LAR) on the road against a defense allowing the third-fewest fantasy points to quarterbacks. Demarcus Robinson (LAR), Tyler Johnson (LAR) and Colby Parkinson (LAR) are all TD-dependent with mild usage in essentially two games without Kupp and/or Nacua.

MINNESOTA AT GREEN BAY

Obvious starters: Justin Jefferson (MIN), Aaron Jones (MIN), Josh Jacobs (GB).

Who to start: Jordan Addison (MIN) maintains WR3/flex upside if he’s active (ankle). I’m not sitting the Vikings D/ST until they give me a reason to. Only Josh Allen, Jayden Daniels and Lamar Jackson have more fantasy points than Sam Darnold (MIN) at quarterback through three weeks. Jordan Love (GB) is an obvious starter if he’s active (knee), although I’d understand if you’d like to give him a week to test the MCL.

Who to sit: Ty Chandler (MIN) is a boom-or-bust option after rushing for 13 yards on seven carries against the Texans last week. Romeo Doubs (GB) and Dontayvion Wicks (GB) would both have flex appeal if Love is active. Christian Watson (GB) remains a boom-or-bust option with only seven targets in three games.

PITTSBURGH AT INDIANAPOLIS

Obvious starters: Steelers D/ST, Jonathan Taylor (IND), Michael Pittman Jr. (IND).

Who to start: George Pickens (PIT) faces a defense allowing the sixth-most fantasy points to wide receivers. Najee Harris (PIT) maintains RB2/flex upside with at least 18 touches in every game this season. We’re due for a Justin Fields (PIT) “smash” game.

Who to sit: Jaylen Warren (PIT) remains TD-dependent with fewer than five touches in two of three games. I’m fading Anthony Richardson (IND) against a defense allowing the fewest fantasy points to quarterbacks.

DENVER AT N.Y. JETS

Obvious starters: Breece Hall (NYJ), Garrett Wilson (NYJ), Jets D/ST.

Who to start: Courtland Sutton (DEN) maintains WR3/flex upside with at least 11 targets in two of three games. Aaron Rodgers (GB) is QB12 over the last two weeks. You could do worse than Tyler Conklin (NYJ) as a streaming option this week.

Who to sit: I’m fading both Javonte Williams (DEN) and Jaleel McLaughlin (DEN) on the road against an elite defense. Bo Nix (DEN) only has value in the deepest Superflex formats until further notice. The Broncos D/ST has been solid so far, but I’m fading them on the road against a resurgent Rodgers.

PHILADELPHIA AT TAMPA BAY

Obvious starters: Saquon Barkley (PHI), Jalen Hurts (PHI), Dallas Goedert (PHI), Mike Evans (TB), Chris Godwin (TB).

Who to start: DeVonta Smith (PHI) is an obvious starter if he’s active (concussion), but it’s not looking good. Rachaad White (TB) maintains RB2/flex upside with at least five receptions in two of three games.

Who to sit: It’s looking like A.J. Brown (PHI) will miss another week (hamstring). The Eagles D/ST only has four sacks in three games. Baker Mayfield (TB) is QB20 over the last two weeks. Bucky Irving (TB) didn’t practice Thursday with a hamstring injury.

CINCINNATI AT CAROLINA

Obvious starters: Ja’Marr Chase (CIN), Joe Burrow (CIN).

Who to start: Tee Higgins (CIN) has WR3/flex upside against a defense that has allowed five TD receptions to wide receivers in three games. Zack Moss (CIN) is the overall RB20 across all fantasy formats through three weeks.

Who to sit: I anticipate Andrei Iosivas (CIN) losing more targets to Higgins in his second game back.

JACKSONVILLE AT HOUSTON

Obvious starters: Travis Etienne (JAC), C.J. Stroud (HOU), Nico Collins (HOU), Stefon Diggs (HOU).

Who to start: Brian Thomas Jr. (JAC) is the overall WR27 in standard formats (WR32 in PPR) through three weeks. After he was non-existent the first two games this season, Christian Kirk (JAC) finished with eight receptions (10 targets) for 79 yards against the Bills last week. The Texans D/ST face an offense allowing the sixth-most fantasy points to opposing defenses.

Who to sit: Let Evan Engram (JAC) test his hamstring in game action before you insert him back into your lineup. Gabe Davis (JAC) remains a boom-or-bust option (same as it ever was) with only eight receptions in three games.

WASHINGTON AT ARIZONA

Obvious starters: Jayden Daniels (WAS), Terry McLaurin (WAS), Brian Robinson (WAS), Kyler Murray (ARI), Marvin Harrison Jr. (ARI), James Conner (ARI).

Who to start: Zach Ertz (WAS) is the overall TE12 in standard formats (TE9 in PPR) through three weeks. Trey McBride (ARI) is an obvious starter if he’s active (concussion).

Who to sit: Austin Ekeler (WAS) remains in the NFL’s concussion protocol. I’m fading a productive Cardinals D/ST at home against a red-hot Daniels.

NEW ENGLAND AT SAN FRANCISCO

Obvious starters: Rhamondre Stevenson (NE), Brandon Aiyuk (SF), 49ers D/ST.

Who to start: George Kittle (SF) is an obvious starter if he’s active (hamstring). Jordan Mason (SF) is the overall RB8 in standard formats (RB14 in PPR) through three weeks.

Who to sit: Hunter Henry (NE) is dealing with an ankle injury and faces a defense allowing the fewest fantasy points to tight ends. Antonio Gibson (NE) only has value in the deepest PPR formats. Ja’Lynn Polk (NE) remains a boom-or-bust option with only six targets in three games.

CLEVELAND AT LAS VEGAS

Obvious starters: Amari Cooper (CLE), Browns D/ST, Davante Adams (LV), Brock Bowers (LV).

Who to start: David Njoku (CLE) is an obvious starter if he’s active (ankle). Jerome Ford (CLE) is the overall RB28 in standard formats (RB24 in PPR) through three weeks.

Who to sit: D’Onta Foreman (CLE) is TD-dependent after producing five yards on two carries against the Giants last week. Gardner Minshew (LV) could be benched soon. I’m fading both Zamir White (LV) and Alexander Mattison (LV) with a difficult matchup.

KANSAS CITY AT L.A. CHARGERS

Obvious starters: Patrick Mahomes (KC), Travis Kelce (KC), Rashee Rice (KC), J.K. Dobbins (LAC).

Who to start: Carson Steele (KC) has flex appeal after receiving 18 touches against the Falcons with Isiah Pacheco sidelined. Quentin Johnston (LAC) has WR3/flex upside with three TD receptions in the last two games.

Who to sit: Xavier Worthy (KC) is a boom-or-bust option against a defense allowing the seventh-fewest fantasy points to wide receivers. Samaje Perine (KC) only has value in the deepest PPR formats. I’d only consider the Chiefs D/ST as a streaming option if Herbert is out.

BUFFALO AT BALTIMORE

Obvious starters: Josh Allen (BUF), James Cook (BUF), Dalton Kincaid (BUF), Lamar Jackson (BAL), Derrick Henry (BAL), Zay Flowers (BAL).

Who to start: Khalil Shakir (BUF) is the overall WR17 across all fantasy formats through three weeks. Mark Andrews (BAL) and Isaiah Likely (BAL) face a defense allowing the eighth-most fantasy points to tight ends -- this matchup could playout similarly to the Ravens’ opener against the Chiefs, which ended up favoring Likely.

Who to sit: Keon Coleman (BUF) remains a boom-or-bust option with only seven targets in three games. It’s probably best to fade the Bills D/ST and Ravens D/ST with these two QBs, but both are certainly capable of making big plays if you can’t find a suitable streaming option.

TENNESSEE AT MIAMI

Obvious starters: Tony Pollard (TEN), Tyreek Hill (MIA), De’Von Achane (MIA).

Who to start: DeAndre Hopkins (TEN) had seven receptions (12 targets) for 124 yards and a TD in a 28-27 win at Miami in Week 14 last season. The Titans D/ST deserve streaming consideration against whomever the Dolphins are lining up under center. If the Titans focus their attention on Hill, Jaylen Waddle (MIA) could still have a big day (especially in PPR) with a lot of work around the line of scrimmage. Raheem Mostert (MIA) has flex appeal if he’s active (chest).

Who to sit: Calvin Ridley (TEN) is a boom-or-bust option with only eight receptions in three games and facing a decent secondary. Jonnu Smith (MIA) faces a defense allowing the second-fewest fantasy points to tight ends.

SEATTLE AT DETROIT

Obvious starters: DK Metcalf (SEA), Amon-Ra St. Brown (DET), Jahmyr Gibbs (DET), David Montgomery (DET).

Who to start: Kenneth Walker (SEA) is an obvious starter if he’s active (oblique). Tyler Lockett (SEA) maintains WR3/flex upside against a defense allowing the third-most fantasy points to wide receivers.

Who to sit: Jaxon Smith-Njigba (SEA) is a boom-or-bust option despite the matchup with three-or-fewer targets in two of three games.