front of a hostile crowd this season — a packed house of 43,024.

“It’s been a while,” said Tommy Edman, whose two-run home run in the ninth inning provided all of the Dodgers’ scoring. “Fortunately, it’s been a good start to the year. We were bound to lose eventually, but still a tough loss, for sure.”

The Dodgers made it tougher by running into outs that ended potential rallies in the eighth and ninth innings.

“Uncharted territory,” Dodgers manager Dave Roberts said with a grin of losing for the first time since Game 2 of the World Series.

“Any loss is tough and I hate losing, we hate losing. But I think it does go to how we play. Today I just think that giving those guys three outs on the bases, it’s hard to win when you play eight innings on the offensive side.”

The first giveaway came in the sixth inning when Andy Pages was picked off first base. Two innings later, singles by Miguel Rojas and Shohei Ohtani put runners at the corners with two outs. Down 3-0, Ohtani tried to steal second with Mookie Betts at the plate and was thrown out by Phillies catcher JT Realmuto to end the inning.

In the ninth, Edman’s homer brought the Dodgers within a run. The Dodgers trailed in six of those eight season-opening wins.

“Up until the final out, we thought we were going to win,” Edman said. “We had some opportunities in the ninth inning, and unfortunately, they just made a few good plays.”

The ending came with a delayed fuse. After Will Smith drew a two-out walk, Chris Taylor pinch-ran for him and seemed to get the trying run into scoring position with a steal of second. After a replay review, though, the call was overturned, ending the game.

“When you give a good team outs and shorten the game, then it’s hard to win. It’s hard to beat a good team. That’s what happened tonight,” Roberts said.

“I just think that with Shohei, in that situation, you got to make sure you’re safe. He’s got the green light. Realmuto is one of the best throwers in the game.”

While winning their first eight games as defending champions, the Dodgers averaged more than 5½ runs per game and hit 18 home runs. They went down meekly against Luzardo on Friday.

The Phillies left-hander retired 16 of the first 17 batters the Dodgers sent up. Only Teoscar Hernandez broke the string with a leadoff single in the second inning. Pages had his one-out walk in the sixth for the Dodgers’ second baserunner, but he was picked off.

“He was good tonight. He was good,” Roberts said of Luzardo. “He flooded the zone. His spin was good tonight. Certainly kept us off-balance, which we had a lot of bad swings. I thought Shohei’s ball, on any normal night, would’ve been a homer. I thought Teo’s ball, any normal night, would’ve been a homer. But you can’t take credit away from Luzardo. He pitched a heck of a ballgame.”

Ohtani’s fly ball to center in the third inning came off the bat at 110.1 mph but died in center field on a windy night.

“I didn’t see any of the metrics on how hard it was blowing, but I think Shohei’s was 110 (mph off the bat) and 32(-degree launch angle) or something like that, which even if there’s a strong wind blowing like that, should be a homer 100% of the time,” Edman said. “So it must have been just howling up there, because, yeah, that ball he hits should be a homer every time.”

Hernandez was the only Dodger who came close to scoring in the first eight innings. He stole second after his second-inning single and flied out to the warning track in left field in the fourth inning. He reached on a two-out bloop double in the seventh inning and stole third. But Kiké Hernandez struck out to strand him.

Dodgers starter Yoshinobu Yamamoto had only a slightly more difficult night than Luzardo’s 95-pitch stroll. The Phillies had runners on base in five of his six innings, but they hit into two double plays and needed help to score their only run against Yamamoto.

Trea Turner doubled down the third-base line in the first inning then broke for third on a steal attempt. Yamamoto spotted him in time, stepped off the rubber and threw toward third. It was not a good throw, though, and got past Miguel Rojas into foul territory as Turner trotted home.