24 points off of the bench while Austin Reaves finished with 13 points, eight assists and six rebounds.
After appearing to hold the left side of his body after the game’s first timeout earlier in the quarter, Davis subbed out at the 2:10 mark of the first as part of the normal rotation and immediately went to the locker room for examination.
Davis, likely to be named a Western Conference reserve for the All-Star Game on Thursday, sat out for the rest of the night.
The Lakers said during the second quarter that Davis was questionable to return because of a strained abdominal muscle before ruling him out at halftime. There was no immediate timeline for Davis’ return to action. How and when he sustained the injury was unclear.
“When our best player goes out, it’s always challenging,” James said. “Especially in the game. If he’s out from the beginning, then we have a game plan set. We know what to expect, we know what our lineup is gonna be. But when A.D. or any one of our guys go down throughout the course of a game, it’s just tough.
“But the level of concern? I think he’ll be fine.”
Davis finished with four points and two rebounds in 10 minutes, one night after recording 42 points and 23 rebounds against the Hornets for the fifth 40-point, 20-rebound game of his career.
After the score was tied at 25 at the end of the first quarter, the 76ers outscored the Lakers 48-32 in the second to take a 73-57 lead into halftime.
“Regardless of who’s playing, we gotta find a way to be better,” Reaves said. “Obviously, it sucks when one of your best players is not available, but got to find a way to be better.”
The Lakers started the third quarter with Dorian Finney-Smith in Davis’ spot along with the starters.
The Lakers didn’t reduce their deficit below 12 points in the second half, with the 76ers — who were without Joel Embiid, Paul George, Andre Drummond, Caleb Martin, KJ Martin and Jared McCain — winning their third consecutive game.
Tyrese Maxey had 43 points on 15-of-26 shooting (4 for 11 from 3-point range) to pace Philadelphia. Kelly Oubre Jr. added 20 points, eight rebounds and five assists while Guerschon Yabusele and Eric Gordon each scored 14 points.
The Lakers also were without Jarred Vanderbilt, the team holding him out on the second night of a back-to-back after he missed the first 42 games of the season following surgery on his feet. Guard Gabe Vincent missed his second consecutive game with knee soreness.
With Vincent out, second-round draft pick Bronny James, the son of LeBron James, was in the Lakers’ first-quarter rotation for the first time.
Bronny missed all five of his shot attempts and turned the ball over three times while also recording three rebounds and an assist in a career-high 15 minutes.