A fugitive from Tennessee wanted on drug charges and two men allegedly possessing guns and drugs were arrested in an early morning raid on a Plymouth motel Friday morning, State Police said.

State Police and Plymouth police executed three search warrants at the Blue Spruce Motel around 4 a.m. Friday after receiving information that someone there was selling methamphetamine, according to police.

As State Police troopers approached the motel, they found Melissa Hinson, 28, of Humboldt, Tenn. — a fugitive wanted on methamphetamine manufacturing charges — sitting in a parked vehicle outside a motel room and arrested her.

Police believe Hinson was staying in the motel room with Jeffrey Shone Haddock, 42, of Hohenwald, Tenn., who was arrested. Troopers also arrested Charles Bradley Barr, 52, of Chocowinity, N.C., who was in an adjoining motel room.

During the execution of the warrants at the motel, troopers discovered a semiautomatic Ruger .380-caliber handgun loaded with five rounds in the magazine, 18.4 grams of methamphetamine, and five oxycodone pills, along with “drug-packaging materials, and scales,’’ according to police.

Additional ammunition was found in one of the suspect’s trucks and $500 of suspected profit from drug sales was seized, police said.

Haddock was charged with unlawful possession of a firearm, unlawful possession of ammunition, and possession of methamphetamine with intent to distribute. Barr faces the same charges, plus a charge of unlawful possession of oxycodone pills.

Haddock and Barr were arraigned in Plymouth District Court. Barr, who is due back in court next Friday, was held on $50,000 bail; Haddock, who is due back in court on Nov. 20, was held on $25,000 bail, according to a spokeswoman from the Plymouth district attorney’s office.

Hinson faces rendition back to Tennessee, police said.

Ben Thompson can be reached at ben.thompson@globe.com. Follow him on Twitter @Globe_Thompson.