Jalen Hurts and Bo Scarbrough each rushed for more than 100 yards Saturday and No. 1 Alabama again got points from its defense and special teams in a 49-10 blowout of No. 9 Tennessee in Knoxville, Tenn.

Alabama (7-0, 4-0 SEC) earned its 19th straight victory overall and its 10th consecutive win in this annual series. Tennessee (5-2, 2-2) has lost its last 13 games against Southeastern Conference Western Division schools.

It was the most lopsided victory by either team in this rivalry since a 51-0 Alabama victory in 1906. Hurts, the Crimson Tide’s freshman quarterback, ran for 132 yards and three TDs as Alabama outrushed Tennessee, 438-32.

Scarborough rushed for 109 yards on just five carries, including an 85-yard touchdown.

Alabama posted its highest single-game rushing total since running for 457 yards in a 56-28 victory over Tennessee in 1986.

The Tide also scored on Ronnie Williams’s 58-yard interception return and Eddie Jackson’s 79-yard punt return. Alabama has 11 non-offensive touchdowns this season, including eight from its defense. The Tide entered the day leading all Football Bowl Subdivision teams in both categories.

Tennessee had erased double-digit deficits in five of its first six games — including a 45-38 loss at Texas A&M last week in which it forced overtime after trailing 28-7 — but the Volunteers couldn’t deliver a similar comeback this time.

Alabama was too good and Tennessee was too hurt.

Tennessee was playing a ranked opponent for the fourth straight week, a stretch that has taken a physical toll.

Injuries decimated the Vols’ defense to such an extent that linebacker Elliott Berry, cornerback Baylen Buchanan and defensive tackle Kahlil McKenzie made their first career starts. McKenzie left in the first quarter after he appeared to hurt his shoulder.

On offense, injuries sidelined guard Jashon Robertson and center Dylan Wiesman for the entire game and knocked out Brett Kendrick in the first quarter. The only starting lineman from last week’s loss to Texas A&M who played the majority of Saturday’s game was right guard Jack Jones.

Ohio State 30, Wisconsin 23 — J.T. Barrett was 17-for-29 passing for 226 yards and hit Noah Brown with a 7-yard TD pass in overtime as the No. 2 Buckeyes (6-0, 3-0 Big 10) held off the No. 8 host Badgers (4-2, 1-2).

Barrett also rushed for two TDs and collected 318 yards in total offense.

Clemson 24, North Carolina State 17 — Deshaun Watson hit Artavis Scott with a 10-yard touchdown pass in overtime and Marcus Edmond finished it with an interception in the end zone as the No. 3 Tigers (7-0, 4-0 ACC) warded off the visiting Wolfpack (4-2, 1-1).

Clemson looked all but done in regulation, but Kyle Bambard’s 33-yard field goal try as time expired was wide right.

Clemson took full advantage with Watson’s strike to Scott. Then Edmond reached high to grab a long throw down the middle from NC State’s Ryan Finley and Clemson had escaped with its path to the ACC title game and the College Football Playoffs still all clear.

Nebraska 27, Indiana 22 — Terrell Newby ran for one score and Tommy Armstrong Jr. hooked up with Stanley Morgan Jr. on a 72-yard TD pass with 9:57 left, helping the No. 10 Cornhuskers (6-0, 3-0 Big Ten) hold off the host Hoosiers (3-3, 1-2) .

Nebraska won its seventh straight game overall and its fifth in a row in this series, last played in 1978. It’s also the first time since 2001 that Nebraska has won its first six.

Baylor 49, Kansas 7 — Seth Russell threw two touchdown passes and ran for two more scores while playing only the first half, Ryan Reid returned the first of his two interceptions for a score, and the No. 11 Bears (6-0, 3-0 Big 12) overwhelmed the Jayhawks (1-5, 0-3).

Shock Linwood’s 4-yard score on the first play after a Kansas fumble was his 36th career rushing touchdown and broke a tie with Alfred Anderson for the most in school history. Linwood was already the career rushing leader for the Bears.

Houston 38, Tulsa 31 — Emeke Egbule returned a fumble 24 yards for a TD with 1:21 left as the No. 13 Cougars (6-1, 3-1 American) beat the visiting Golden Hurricane (4-2, 1-1).

The game was tied at 31-31 when Garrett Davis knocked the ball out of the hands of quarterback Dane Evans. Egbule scooped it up and dashed into the end zone for the score.

Tulsa had a chance to tie it, but Jesse Brubaker was stopped just short of the goal line after a reception on the last play of the game to seal Houston’s victory. The play was reviewed and upheld.

Florida State 17, Wake Forest 6 — Travis Rudolph had a career-high 13 receptions for 238 yards as the No. 14 Seminoles (5-2, 2-2 ACC) overcame three turnovers to defeat the visiting Demon Deacons (5-2, 2-2).

Deondre Francois accounted for both of Florida State’s touchdowns. His 2-yard run on a quarterback keeper with 3:16 remaining in the second quarter gave the Seminoles a 10-3 lead. The touchdown was set up after Wake Forest punter Dom Maggio fumbled the snap, which Amir Rasul recovered at the Wake 26.

North Carolina 20, Miami 13 — Mitch Trubisky threw two touchdown passes and Malik Carney forced a turnover with 1:31 left as the visiting Tar Heels (5-2, 3-1 ACC) denied the 16th-ranked Hurricanes (4-2, 1-2) their last chance at a rally.

Ryan Switzer and Austin Proehl had scoring catches for North Carolina. Bug Howard added 10 catches for 156 yards.

Trubisky completed 33 of 46 passes for 299 yards.

Mark Walton rushed for 82 yards and Joe Yearby ran for 74 more and a touchdown for Miami, which lost its second straight game after last week’s 20-19 loss to Florida State.

Syracuse 31, Virginia Tech 17 — Eric Dungey accounted for 417 yards and two touchdowns and the host Orangemen (3-4, 1-2 ACC) beat the No. 17 Hokies (4-2, 2-1) for their first victory over a ranked opponent since 2012.

Fans stormed the field and carried off Dungey in celebration after he passed for 311 yards and ran for 106. He scored on a 1-yard sneak to give Syracuse a 24-17 lead with 7:56 to go, and hit Erv Phillips on a 58-yard TD pass in the first quarter.