Two of the NFL’s top young quarterbacks suffered broken legs on Saturday.

The Raiders’ Derek Carr was hurt in the fourth quarter of Oakland’s 33-25 win over the Colts, twisted to the ground by Indianapolis linebacker Trent Cole on a sack. Carr stayed on the ground for several minutes in pain as trainers came out to treat him, and he was carted off the field.

Raiders coach Jack Del Rio announced the severity of Carr’s injury after the game, and said Carr will have surgery Sunday for a broken right fibula and is out indefinitely. The Raiders are headed to the playoffs for the first time since 2002.

‘‘As soon as I got out there, he said, ‘I think it’s broken,’ ’’ Del Rio said.

‘‘Seeing him go down like that, it hurt us,’’ linebacker Bruce Irvin said. ‘‘It didn’t even feel like we won.’’

Fourth-year quarterback Matt McGloin took over for Carr and was 2 of 3 for 29 yards.

A few hours earlier, Titans quarterback Marcus Mariota broke his right fibula in a 38-17 loss to Jacksonville. Coach Mike Mularkey said Mariota will need a minimum of six weeks to recover.

Mariota was injured late in the third quarter when Jaguars rookie Sheldon Day sacked him as he scrambled on a first-down throw, grabbing him around the ankles. The quarterback signaled to the Tennessee sideline and pounded the ground as trainers rushed to his side. They positioned an air cast on his leg and lifted Mariota onto a cart.

Teammates and even some Jaguars patted Mariota on the shoulders before he exited.

‘‘That breaks my heart, man,’’ Titans offensive tackle Taylor Lewan said. ‘‘Love him. That guy’s an awesome dude. For that to happen to him, it’s unfair.’’

Matt Cassel will be Tennessee’s starting quarterback for next week’s regular-season finale against Houston and into the playoffs, if the Titans make it. Cassel finished Saturday’s game 13 of 24 for 124 yards, with a TD pass to Delanie Walker as well as a pick.

Mariota completed 8 of 20 passes for 99 yards and a touchdown before the injury.

He had a 3-yard scoring pass to Rishard Matthews in the second quarter, but he spent much of his day hurried and throwing high and low.

‘‘We didn’t protect him — offensive line, running backs — we didn’t protect him all day,’’ Titans running back DeMarco Murray said.

Mariota missed the final two games of the 2015 season with a sprained knee.

Mariota completed 61.2 percent of his passes this season for 3,426 yards, with 26 touchdown throws and nine interceptions. He also ran for two scores.

‘‘I think everybody to a man went to see him in the training room and wished him well,’’ Cassel said.

The former Patriot started eight games last season for Buffalo and Dallas, going 2-6.

High marks

Two other quarterbacks earned more positive headlines Saturday.

The Falcons’ Matt Ryan threw two touchdown passes in a 33-16 win at Carolina, giving him 33 for the season. That broke his own franchise record of 32, which he set in 2012. Ryan’s two scoring throws went to tight ends Joshua­ Perkins and D.J. Tialavea, who was signed from the practice squad earlier in the week. In so doing, Ryan set an NFL season record by throwing at least one touchdown pass to 13 different receivers.

Aside from his sparkling performance in a 38-25 victory over the Vikings — 347 yards passing, four TDs — Aaron Rodgers grabbed a spot in the Packers’ record book by hooking up with Jordy Nelson for their 58th and 59th touchdowns as teammates. They entered the day tied with the duo of Brett Favre and Antonio Freeman.

Rodgers shook off a right calf injury he sustained late in the second quarter.

‘‘Once I got moving, I felt like myself,’’ said Rodgers.

It’s not how you start

The Vikings’ season was already going downhill long before their team plane got stuck in the grass on the way to the gate at a Wisconsin airport on Friday night after making a safe landing, forcing a delay of more than five hours.

Now Minnesota (7-8) is out of the playoff race. Saturday’s loss at Green Bay sealed that fate, even after the Vikings started the season 5-0.

‘‘I think when you look at it, there were just a lot of mistakes, self-inflicted wounds and they came back to bite us and we weren’t able to overcome those at times,’’ quarterback Sam Bradford said of the team’s slide.

Minnesota outgained the Packers, 446-348, but made too many mistakes to catch up.

‘‘Trying to think of all them but there was a lot,’’ said coach Mike Zimmer.

Concern for Floyd

Leonard Floyd has provided flashes of hope throughout another lost year for the Bears, but there’s now reason for concern as the season winds down.

Floyd, a rookie linebacker, was sidelined by a concussion for the second time in a month in the first half of Chicago’s 41-21 loss to Washington Saturday.

That is prompting questions about potential long-term health issues.

‘‘I get concerned about any player that gets injured, not just Leonard,’’ coach John Fox said. ‘‘It is a physical game and injuries are part of it. I don’t want to single one guy out.’’

It was unclear exactly when Floyd got hurt. He was carted off from the sideline early in the second quarter with a towel over his head.

There were questions about Floyd’s size (6 feet 6 inches, 240 pounds) and strength heading into the draft, and he also had surgery on each shoulder during his career at Georgia. But the Bears traded up to grab him ninth overall.

Floyd is tied for second on the Bears with seven sacks in 12 games.

But he also was evaluated for a concussion after a scary collision late in a Nov. 20 loss to the Giants sent him to the hospital. He missed one game with a neck injury.