A Boston man who was charged in 2002 with the brutal murder of his mother and acquitted by reason of insanity returned to court Wednesday for arraignment on new charges of assaulting his girlfriend and two police officers.

Carlos Lugo, 43, pleaded not guilty in Suffolk Superior Court to charges including assault and battery on a disabled person, malicious destruction of property, and assault and battery on a police officer. He was held on $25,000 bail.

Assistant Suffolk District Attorney Ursula Knight told the court the alleged victim in the new case is deaf and cannot speak.

“There’s clearly a repetitive nature to the allegations in this case,’’ Knight said, adding that Lugo has a “significant mental health history’’ and a lengthy criminal record that includes the murder charge.

After his acquittal in that case, Knight said, Lugo was held at Bridgewater State Hospital before being released.

Accused killers found not guilty by reason of insanity can be held at Bridgewater indefinitely. They can seek their release through a court process and are freed if they’re no longer deemed to present a public safety threat.

During Lugo’s 2002 arraignment, Suffolk Assistant District Attorney John Pappas disclosed chilling details of the slaying of Lugo’s mother, 50-year-old Josefina Lugo.

“It doesn't get any worse than this," Pappas told the court at the time.

Authorities at the time said police arrived at the St. Cyprian’s Place apartment that Carlos Lugo and his mother shared to find Josefina Lugo lying face up on the sidewalk with puncture wounds to her chin and missing teeth. Her head had been battered, and officers thought she might have been tossed out the window from her apartment four stories above.

Upstairs, her blood was splattered on the walls and on a lightbulb near the ceiling, and her teeth were on the floor. Her son, then 27, sat in a bedroom with his knuckles and arm bleeding and his boots soaked in blood, authorities said.

Pappas said only a “very depraved individual’’ could deliver such a merciless beating to Josefina Lugo, who sustained “massive’’ head injuries.

Lugo’s mental health problems factored into his eventual acquittal. A forensic psychologist said during the murder arraignment that he hallucinates, suffers time lapses, and is paranoid, and that he didn’t appear to understand the charges that were filed.

During Wednesday’s arraignment in the assault case, Knight said Lugo’s girlfriend had reported that he sometimes goes off his medication and lapses into a “catatonic’’ state before “becoming enraged, then lashing out.’’

Lugo is currently charged in connection with three incidents that occurred late last year. He’s been held for the past two months after violating terms of his earlier bail set in district court, according to officials.

Incident reports filed in the case said police responded to the girlfriend’s East Boston residence on the afternoon of Aug. 17, 2017, after her brother told officers she was “having [an] issue with her boyfriend being violent towards her.’’

The alleged victim indicated, by writing and using hand gestures, that she and Lugo had argued and she wanted to end the relationship.

She said Lugo became angry and started “to throw things about the room’’ and punched a hole in a television set, a report said.

Lugo was placed into custody.

Then on Sept. 1, police returned to the address, where the girlfriend and a resident service coordinator reported that Lugo “shoved the victim twice during a dispute,’’ records show. Police learned that the woman had taken out a restraining order against Lugo following his August arrest but later asked a judge to lift the order. Lugo wasn’t present.

He landed back in custody Nov. 3, when officers returned to the alleged victim’s residence, and she said she had argued with Lugo again and wanted him out. She said Lugo had insulted her, snatched a check out of her hand, and took her cellphone, according to records.

She said she was “physically intimidated by the suspect due to his large physical stature, tone of voice, and mannerisms,’’ according to a report.

As police escorted Lugo from the apartment, he suddenly began to run, leading them on a brief foot chase into a courtyard, according to a filing.

Lugo then “turned around, shoved both officers and began to strike the officers by swinging his arms,’’ the report said. “Officers were able to grapple the suspect to the ground, at which point he locked both of his arms underneath his 300 [pound] frame.’’

Aaron Lazar, a court-appointed lawyer for Lugo, requested Wednesday that his client be released on personal recognizance. He said Lugo is a diagnosed schizophrenic who had been addressing his mental health issues before going off his medications.

Lugo’s next court date is June 25.

Travis Andersen can be reached at travis.andersen@globe.com. Michael S. Rosenwald formerly of the Globe staff contributed to this report.