FOXBOROUGH — Peanut butter and jelly. Bacon and eggs. Macaroni and cheese. Louisiana Tech quarterback Ryan Higgins and wide receiver Carlos Henderson.

Some things just work well together.

Higgins and Henderson combined for five touchdowns in a 56-28 rout of the Minutemen Saturday at Gillette Stadium, spoiling UMass’s final game on the Patriots’ turf this season.

“Without question Henderson was the best player on the field and we didn’t have an answer for him,’’ UMass coach Mark Whipple said. “We weren’t good enough to beat those guys today.’’

For Louisiana Tech (4-3), Higgins finished 26 of 33 for 484 passing yards and five touchdowns with one interception. Henderson made 12 catches for 326 yards and senior wide receiver Trent Taylor logged 126 receiving yards on nine catches.

UMass quarterback Andrew Ford completed 29 of 40 passes for 268 yards and three TDs. He was intercepted once and sacked seven times.

“He did a lot of good things,’’ Whipple said of Ford. “He played like a real good quarterback for most of the game and then at other times he played like a guy that’s never been coached.’’

Higgins needed just 1:15 and three plays to get the Bulldogs into the end zone. After a completion to Taylor and a rush by junior Jarred Craft, Higgins found Henderson, Henderson found the holes in the UMass defense, and Louisiana Tech was on the board with a 50-yard touchdown.

The Minutemen defense woke up on the next Louisiana Tech drive. Sha-Ki Holines and Peter Angeh teamed to sack Higgins for a loss of 7 yards on second down, and an incompletion on third and 14 forced a punt.

A 41-yard punt return by James Allen put UMass in Bulldogs’ territory to start the ensuing drive.

Six plays and 48 yards later, the game was tied. Marquis Young got inside the right corner of the end zone for a 9-yard score. Mike Caggiano kicked the extra point.

UMass’s offense was cruising late in the first quarter and began the second frame on the Louisiana Tech 3-yard line. But the promising drive quickly fell apart. A holding call and a sack of Ford pushed the Minutemen back to the 16 on fourth down. Caggiano’s attempt at a 33-yard field goal wobbled wide right.

On the next Louisiana Tech possession, the UMass bench was whistled for an unsportsmanlike conduct penalty that turned third and 16 into third and 1 from the UMass 26. But Taylor fumbled after a 15-yard catch and junior linebacker Colbert Calhoun recovered for the Minutemen.

UMass couldn’t capitalize on the turnover and was forced to punt.

Higgins then ran two plays in 37 seconds to put Louisiana Tech back on top. The quarterback first connected with Craft for 12 yards, then completed a pass to Henderson for a 42-yard touchdown. The extra point by Jonathan Barnes gave the Bulldogs a 14-7 lead with 6:21 to go before halftime.

With 1:54 left in the second quarter, Louisiana Tech sophomore Kam McKnight fought off Khary Bailey-Smith to get across the goal line for a 3-yard touchdown, finishing off a seven-play, 48-yard drive.

Less than a minute later, Ford hit senior Dan Jonah with an 18-yard touchdown pass to pull UMass within a score, but with five seconds to go in the quarter, Higgins tossed another touchdown pass to — you guessed it — Henderson. The 5-yard catch gave the Bulldogs a 28-14 halftime lead.

“They have a lot of talented players but we made too many mistakes and missed too many tackles,’’ said UMass linebacker Steve Casali. “If you make too many mistakes against a team like that, you’ll pay for it.’’

UMass received to start the second half and missed another field goal on its first drive. Logan Laurent came out to try a 36-yarder, but the kick was low and outside the left goal post.

The Minutemen scored a touchdown after recovering a Louisiana Tech fumble. Ford needed just one play, firing a 14-yard touchdown pass to a wide open John Robinson-Woodgett.

But the Higgins-to-Henderson connection came through again for the Bulldogs, answering the UMass touchdown with an 83-yard score.

Louisiana Tech extended its lead when Ford fumbled as he was sacked by sophomore Jaylon Ferguson. Junior linebacker Russell Farris finished the play with a 19-yard scoop and score to put the Bulldogs ahead, 42-21, with 11:08 to go in the third.

“The fumble was kind of a dagger,’’ Whipple said.

Henderson caught a 6-yard touchdown pass with 10:36 to play and junior Boston Scott added a 71-yard touchdown run with 6:20 remaining.

Ford tacked on a late score for the Minutemen with a 5-yard touchdown pass to Andy Isabella.

“There are times in games where we feel like we can play with anybody in the country,’’ Ford said. “We just have to — we say it every week — have to learn from our mistakes, and make sure we’re making more plays than mistakes.’’

Emily McCarthy can be reached at emily.mccarthy@globe.com. Follow her on Twitter @emilymccarthy.